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100% body weight walking for Osteoarthritis (LBPPKNEEOA Trial)

N/A
Waitlist Available
Led By Prakash Jayabalan, MD, PhD
Research Sponsored by Shirley Ryan AbilityLab
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, and 45 minutes of walking
Awards & highlights

LBPPKNEEOA Trial Summary

This study is evaluating whether a specific type of exercise may help reduce joint pain for individuals with osteoarthritis.

Eligible Conditions
  • Osteoarthritis

LBPPKNEEOA Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, and 45 minutes of walking
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, and 45 minutes of walking for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Cartilage oligomeric matrix protein serum concentration
Change in Knee Joint Pain
Secondary outcome measures
Change in Inflammatory cytokine (IL-6, IL-1B and TNF-A) concentration

LBPPKNEEOA Trial Design

2Treatment groups
Experimental Treatment
Group I: 50% body weight walkingExperimental Treatment1 Intervention
Individuals with knee osteoarthritis will walk 45 minutes on a treadmill at 50% full body weight loading
Group II: 100% body weight walkingExperimental Treatment1 Intervention
Individuals with knee osteoarthritis will walk 45 minutes on a treadmill at 100% full body weight loading

Find a Location

Who is running the clinical trial?

Shirley Ryan AbilityLabLead Sponsor
195 Previous Clinical Trials
16,904 Total Patients Enrolled
3 Trials studying Osteoarthritis
133 Patients Enrolled for Osteoarthritis
Prakash Jayabalan, MD, PhD5.02 ReviewsPrincipal Investigator - Shirley Ryan AbilityLab
Shirley Ryan AbilityLab
3 Previous Clinical Trials
133 Total Patients Enrolled
3 Trials studying Osteoarthritis
133 Patients Enrolled for Osteoarthritis
5Patient Review
This doctor is incredible! They were so knowledgeable and had great bedside manner. They actually spoke to me on the phone, which I really appreciated. I would highly recommend them to anyone!

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Positive Pressure Treadmill Walking for Individuals With Knee Pathology
Prakash Jayabalan MD, PhD 2019. "Positive Pressure Treadmill Walking for Individuals With Knee Pathology". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04747444.
All > Pathology
~5 spots leftby May 2025
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