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Cell Therapy

ERIPTO Protocol for Osteoarthritis (ERIPTO Trial)

N/A
Waitlist Available
Led By Mohammed M Qureshi, DO, CAQSM, MRO
Research Sponsored by Affinity Health Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

ERIPTO Trial Summary

This trial is comparing two different treatments for post-traumatic osteoarthritis of the knee, one involving a bone marrow aspirate concentrate (BMAC) and one involving the ERIPTO protocol. The investigators will be looking at various factors such as time frame from initial injury, type of injury, gender, and age when injury first occurred to see if there is a correlation with the severity of osteoarthritis.

Eligible Conditions
  • Osteoarthritis

ERIPTO Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Radiographic Changes
Secondary outcome measures
Subjective Knee Symptom Changes

ERIPTO Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: ERIPTO ProtocolExperimental Treatment1 Intervention
Protocol arm actively being studied
Group II: BMAC onlyActive Control1 Intervention
bone marrow aspirate concentrate only arm

Find a Location

Who is running the clinical trial?

Affinity Health Research InstituteLead Sponsor
The Center for Primary Care and Sports MedicineUNKNOWN
Genesis Orthopedics and Sports MedicineUNKNOWN

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Michigan
How old are they?
18 - 65
What site did they apply to?
Genesis Orthopedics and Sports Medicine
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
CartilageJournal
One-step Cartilage Repair with Bone Marrow Aspirate Concentrated Cells and Collagen Matrix in Full-thickness Knee Cartilage Lesions
Gobbi, Alberto, Georgios Karnatzikos, Celeste Scotti, Vivek Mahajan, Laura Mazzucco, and Brunella Grigolo. 2011. “One-step Cartilage Repair with Bone Marrow Aspirate Concentrated Cells and Collagen Matrix in Full-thickness Knee Cartilage Lesions”. Cartilage. SAGE Publications. doi:10.1177/1947603510392023.
Experimental Cell ResearchJournal
Platelet Rich Plasma (PRP) Induces Chondroprotection via Increasing Autophagy, Anti-inflammatory Markers, and Decreasing Apoptosis in Human Osteoarthritic Cartilage
Moussa, Mayssam, Daniel Lajeunesse, George Hilal, Oula El Atat, Gaby Haykal, Rim Serhal, Antonio Chalhoub, Charbel Khalil, and Nada Alaaeddine. 2017. “Platelet Rich Plasma (PRP) Induces Chondroprotection via Increasing Autophagy, Anti-inflammatory Markers, and Decreasing Apoptosis in Human Osteoarthritic Cartilage”. Experimental Cell Research. Elsevier BV. doi:10.1016/j.yexcr.2017.02.012.
Journal of Orthopaedic & Sports Physical TherapyJournal
Sports, Joint Injury, and Posttraumatic Osteoarthritis
Buckwalter, Joseph A.. 2003. “Sports, Joint Injury, and Posttraumatic Osteoarthritis”. Journal of Orthopaedic & Sports Physical Therapy. Journal of Orthopaedic & Sports Physical Therapy (JOSPT). doi:10.2519/jospt.2003.33.10.578.
Journal of Bone and Joint SurgeryJournal
Adult Human Mesenchymal Stem Cells Delivered via Intra-articular Injection to the Knee Following Partial Medial Meniscectomy
Vangsness, C. Thomas, Jack Farr, Joel Boyd, David T. Dellaero, C. Randal Mills, and Michelle LeRoux-Williams. 2014. “Adult Human Mesenchymal Stem Cells Delivered via Intra-articular Injection to the Knee Following Partial Medial Meniscectomy”. Journal of Bone and Joint Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.2106/jbjs.m.00058.
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