Cryoneurolysis for Knee Pain
Trial Summary
Do I need to stop my current medications for the trial?
The trial requires that you are not currently using opioids. If you are taking opioids, you would need to stop before participating.
What data supports the effectiveness of the treatment Iovera - Cryoneurolysis for knee pain?
How does the treatment Iovera - Cryoneurolysis for knee pain differ from other treatments?
Cryoneurolysis is unique because it uses freezing temperatures to temporarily block nerve signals, providing pain relief for weeks to months without permanent nerve damage. This method is different from other treatments like local anesthetic nerve blocks, which typically offer shorter-term relief.12346
What is the purpose of this trial?
This trial is testing a device called Iovera that freezes pain-causing nerves to help people who are having knee replacement surgery. The goal is to reduce pain and the need for opioid medications after surgery. The study will see if this method can make recovery easier and faster.
Eligibility Criteria
Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Preoperative Treatment
Participants receive cryoneurolysis treatment using the Iovera device or placebo prior to surgery
Postoperative Follow-up
Participants are monitored for pain management, function, and opioid consumption
Treatment Details
Interventions
- Iovera - Cryoneurolysis
- Local anesthetic
Find a Clinic Near You
Who Is Running the Clinical Trial?
Unity Health Toronto
Lead Sponsor