Mindset for Malignancies

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Stanford University, Stanford, CA
Malignancies
Mindset - Other
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

Leveraging Mindsets to Improve Health and Wellbeing in Patients With Cancer

See full description

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Mindset will improve 1 primary outcome and 7 secondary outcomes in patients with Malignancies. Measurement will happen over the course of 6 weeks.

6 weeks
Biomarker Analyses
Fear of Cancer Recurrence
Measuring affect with cancer
Measuring coping with cancer
Measuring emotional regulation with cancer
Measuring mindsets
Measuring stress with cancer
Quality of Life Survey

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Treatment As Usual (TAU)
1 of 2
Mindset Intervention
1 of 2
Active Control
Experimental Treatment

This trial requires 120 total participants across 2 different treatment groups

This trial involves 2 different treatments. Mindset is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Mindset InterventionMindset Intervention will include watching three brief ~10-25 minute films and respond to a number of short reflection activities after viewing the films.
Treatment As Usual (TAU)
Other
TAU Control Arm will complete the same assessments as those participants in the Mindset Intervention Arm, but will not view the short films or complete the corresponding response activities.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 6 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 6 weeks for reporting.

Closest Location

Stanford University - Stanford, CA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. You must have received newly diagnosed for Malignancies. There are 6 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Patients diagnosed with lung cancer, breast cancer, GI/Colorectal cancer, or Lymphoma to be treated with curative intent will be eligible for this study.
Participants will be recruited if they are receiving at least one course of systemic treatment. As we are recruiting participants near the point of diagnosis, we will target individuals who have not received prior therapy for cancer.
Neither ECOG or Karnofsky Performance Status will be employed
Ability to understand and willingness to sign a written informed consent document is required for participation in this study.
Treatment plan includes course of systemic treatment involving no less than 4 and no more than 12 infusions.
We will only recruit patients ≥ 18 years who are fluent in English and are without cognitive impairment. We have no gender, race, or ethnicity restrictions. Diagnosis of cancer (breast, lung, GI or colorectal, or lymphoma) and treatment given with curative intent.

Patient Q&A Section

What are the signs of malignancies?

"Patients with a benign disorder present with a wide variety of nonspecific symptoms. In all cases an underlying malignant disorder with characteristic manifestations may be inferred." - Anonymous Online Contributor

Unverified Answer

How many people get malignancies a year in the United States?

"The incidence of cancers is rising worldwide but in the United States malignancies are most common in the older population. It is estimated that 19% of men and 32% of women will die of cancer at some time in their lives." - Anonymous Online Contributor

Unverified Answer

What are common treatments for malignancies?

"There are many medications that can be used to treat various cancers. The most common cancer treatments include medications for leukemia and medications used to treat non-Hodgkin's lymphoma. Other chemotherapy drugs may be used to treat testicular cancer and lung cancer, including cisplatin, carboplatin, bleomycin, and paclitaxel. Other treatments may include radiation, surgery for cancers, and hormonal therapy for cancer. There might also be chemotherapy drugs that focus on the treatment of ovarian cancer and endometrial cancer. Treatment and diagnosis can be done using radiology for imaging of brain, spine, and cancer and other conditions. Medication and radiation is commonly used to treat some cancers." - Anonymous Online Contributor

Unverified Answer

Can malignancies be cured?

"No statistically significant reductions in cancer burden could be demonstrated, with some increase in cancer burden on children aged 1 to 4 years. This might have important implications for children treated with radiotherapy." - Anonymous Online Contributor

Unverified Answer

What causes malignancies?

"Although viral infection is known to have an association with cancers of the breast, thyroid and other tissues, there is limited research available to confirm evidence of a causal relationship between hepatitis B virus (HBV) and cancer. More recent evidence has suggested that HBV may increase the likelihood of the development of primary liver cancer, which increases the risk of hepatocellular carcinoma (HCC), the most important form of liver cancer in the developing countries." - Anonymous Online Contributor

Unverified Answer

What is malignancies?

"A malignancy is an abnormal growth or excessive enlargement of a cell or cells of a tissue. Usually, when referring to a malignancy, it is an uncontrolled and fast growing tissue that has spread to other areas of the body or to distant parts of the body. In the US, cancers that can be definitively distinguished from benign conditions have become more and more common since the 1960s.\n" - Anonymous Online Contributor

Unverified Answer

What are the common side effects of mindset?

"In a recent study, findings indicate that symptoms in both the present and the previous week, and not just in recent weeks are more prevalent in patients with mindset compared to those without mindset. This points out to possible factors other than mindset to account for symptoms." - Anonymous Online Contributor

Unverified Answer

Who should consider clinical trials for malignancies?

"Patient selection is the most important criterion to define patient eligibility for clinical trials. Clinical trial design should encourage high-quality trials for patients with specific conditions; clinicians should consider clinical trials especially for patients who have specific prognostic factors associated with trial outcome. Better clinical trial design may lead to higher enrollment rates, better care and lower cost by reducing delays in the treatment, or increase patient satisfaction by reducing waiting times." - Anonymous Online Contributor

Unverified Answer

How serious can malignancies be?

"There are many conditions affecting patients suffering from malignancies. They are often serious, especially in cases related to the cardiovascular system, respiratory tract, and skin. These conditions may even lead to death in some patients. However, it is difficult to predict which malignancies will progress for some time in any particular patient." - Anonymous Online Contributor

Unverified Answer

Does malignancies run in families?

"We demonstrated that the occurrence of a first-degree relative with cancer was significantly greater in families with multiple cases of breast cancer and also increased for families with multiple occurrences of renal cell cancer. The odds ratios for those with other cancers (including cervical and lung cancers) were also significantly increased. If the first-degree relative with cancer is a parent, then children may be exposed to an increased risk of developing the underlying cancer." - Anonymous Online Contributor

Unverified Answer

What is mindset?

"Clinicians should be aware that an adequate mindset is important for effective communication and clinical treatment. We suggest that clinicians should (1) check their own thinking process and (2) pay attention to each patient's mindset in order to improve communication with the patient." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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