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Electrical Stimulation

Noxious Electrical Stimulation (NxES) for Osteoarthritis

N/A
Waitlist Available
Led By Scott K Stackhouse, PT, PhD
Research Sponsored by University of New England
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up aim 1: assessed at baseline, immediately post-treatment, 24- and 72-hours post-treatment. aim 2: assessed at baseline, at 72-hours after final intervention, and 4-weeks post-intervention.
Awards & highlights

Study Summary

Influence of Noxious Electrical Stimulation on Chronic Pain From Knee Osteoarthritis

Eligible Conditions
  • Osteoarthritis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~aim 1: assessed at baseline, immediately post-treatment, 24- and 72-hours post-treatment. aim 2: assessed at baseline, at 72-hours after final intervention, and 4-weeks post-intervention.
This trial's timeline: 3 weeks for screening, Varies for treatment, and aim 1: assessed at baseline, immediately post-treatment, 24- and 72-hours post-treatment. aim 2: assessed at baseline, at 72-hours after final intervention, and 4-weeks post-intervention. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Brief Pain Inventory (BPI)
Change in Intermittent and Constant Osteoarthritis Pain scale (ICOAP)
Change in Movement-Related Pain
+1 more
Secondary outcome measures
Change in Conditioned Pain Modulation (CPM)
Change in Five-Times Sit-to-Stand (5xSTS) Test
Change in Heat Temporal Summation (HTS)
+2 more
Other outcome measures
Brief Resiliency Scale (BRS)
Anxiety
Pain Catastrophizing Scale (PCS)
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Noxious Electrical Stimulation (NxES)Experimental Treatment1 Intervention
The NxES intervention will be applied for a single treatment in Aim 1 and after a washout period, will be applied 3x/week for 2-weeks (6 sessions) for Aim 2.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Noxious Electrical Stimulation (NxES)
2021
N/A
~20

Find a Location

Who is running the clinical trial?

University of New EnglandLead Sponsor
15 Previous Clinical Trials
1,900 Total Patients Enrolled
Scott K Stackhouse, PT, PhDPrincipal InvestigatorUniversity of New England

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~4 spots leftby Apr 2025