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Prebiotic

Prebiotic oligofructose-enriched inulin for Obesity

N/A
Waitlist Available
Led By Raylene A Reimer, PhD, RD
Research Sponsored by University of Calgary
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 6 months
Awards & highlights

Study Summary

This trial will test whether prebiotics can improve knee function and reduce pain in obese adults with metabolic knee osteoarthritis.

Eligible Conditions
  • Obesity
  • Osteoarthritis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in 30 second chair stand test
Change in 40 metre fast based walk
Change in 6 minute walk test
+2 more
Secondary outcome measures
Change in body fat
Change in fecal microbiota composition
Change in fecal short chain fatty acids (SCFA) concentration
+8 more
Other outcome measures
Change in gastrointestinal comfort

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: PrebioticExperimental Treatment1 Intervention
Two 8g doses/day (12 kcal/dose) of oligofructose-enriched inulin
Group II: PlaceboPlacebo Group1 Intervention
Two 3.3g doses/day (12 kcal/dose) of maltodextrin
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Prebiotic oligofructose-enriched inulin
2018
N/A
~60

Find a Location

Who is running the clinical trial?

University of CalgaryLead Sponsor
792 Previous Clinical Trials
869,100 Total Patients Enrolled
14 Trials studying Obesity
1,102 Patients Enrolled for Obesity
Raylene A Reimer, PhD, RDPrincipal InvestigatorUniversity of Calgary
6 Previous Clinical Trials
413 Total Patients Enrolled
2 Trials studying Obesity
174 Patients Enrolled for Obesity

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
TrialsJournal
Effect of a Prebiotic Supplement on Knee Joint Function, Gut Microbiota, and Inflammation in Adults with Co-morbid Obesity and Knee Osteoarthritis: Study Protocol for a Randomized Controlled Trial
Fortuna, Rafael, David A. Hart, Keith A. Sharkey, Rachel A. Schachar, Kelly Johnston, and Raylene A. Reimer. 2021. “Effect of a Prebiotic Supplement on Knee Joint Function, Gut Microbiota, and Inflammation in Adults with Co-morbid Obesity and Knee Osteoarthritis: Study Protocol for a Randomized Controlled Trial”. Trials. Springer Science and Business Media LLC. doi:10.1186/s13063-021-05212-w.
clinicaltrials.govStudy
Effect of Prebiotics on Function and Pain in Patients With Osteoarthritis and Obesity
Dr. Raylene Reimer 2018. "Effect of Prebiotics on Function and Pain in Patients With Osteoarthritis and Obesity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04172688.
~8 spots leftby Apr 2025
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