Minds and Mentors for Opioid Use Disorder

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Opioid Use Disorder+2 MoreMinds and Mentors - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the effectiveness of the Minds and Mentors Program (MiMP) in treating individuals with opioid use disorder. The study will compare the MiMP to Twelve Step Facilitation, and will measure outcomes such as adherence to medication, rates of relapse and cravings, and self-reported anxiety, stress, and depression. Additionally, the trial will examine whether pre-intervention cortisol reactivity is predictive of relapse outcomes, and/ or whether reductions in cortisol reactivity over the course of intervention mediate relapse outcomes.

Eligible Conditions
  • Opioid Use Disorder
  • Substance Use Disorder
  • Medication Assisted Treatment

Treatment Effectiveness

Study Objectives

1 Primary · 6 Secondary · Reporting Duration: 9 months

9 months
Adherence Rate
Anxiety
Cortisol Reactivity
Cravings
Depression
Quality of Life
Relapse
Stress

Trial Safety

Trial Design

2 Treatment Groups

12 Step Treatment Program
1 of 2
Mindfulness based relapse prevention and peer mentoring
1 of 2

Active Control

Experimental Treatment

240 Total Participants · 2 Treatment Groups

Primary Treatment: Minds and Mentors · No Placebo Group · N/A

Mindfulness based relapse prevention and peer mentoring
Behavioral
Experimental Group · 1 Intervention: Minds and Mentors · Intervention Types: Behavioral
12 Step Treatment Program
Behavioral
ActiveComparator Group · 1 Intervention: Twelve Step Intervention Group · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 9 months

Who is running the clinical trial?

University of Alabama at BirminghamOTHER
1,437 Previous Clinical Trials
2,229,104 Total Patients Enrolled
Tuscaloosa Veterans Affairs Medical CenterFED
5 Previous Clinical Trials
453 Total Patients Enrolled
University of Alabama, TuscaloosaLead Sponsor
33 Previous Clinical Trials
16,184 Total Patients Enrolled
Pathway Healthcare, LLCUNKNOWN

Eligibility Criteria

Age 18+ · All Participants · 9 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are able to provide written informed consent.\n
You have had an opioid use disorder diagnosis based on DSM-V criteria in the past 30 days.
You are in maintenance phase of MOUD.