Hydrocolloid Dressings for Facial Reconstruction

(HCD Wound Heal Trial)

Overseen By Connie Dampier

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Janice Hernandez, MD

Disqualifiers: Under 18, Over 100, Allergy, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: 1 week

20 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a new method for caring for facial surgery wounds using a hydrocolloid dressing, which may be easier than the usual ointment method. The goal is to determine if this bandage can simplify healing with less hassle for patients after surgery. Participants will receive either the new bandage or the regular ointment to compare results. Individuals who have undergone facial surgery and seek a potentially easier recovery might be suitable, provided they can attend follow-up visits and have no allergies to the bandage materials. As an unphased trial, this study allows participants to contribute to innovative wound care research that could simplify recovery for future patients.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that hydrocolloid dressings are safe for facial reconstruction?

A previous study showed that hydrocolloid dressings effectively prevent facial ulcers and aid in wound healing after surgery. Research indicates that patients generally tolerate these dressings well, with few side effects. Their successful use in other facial surgeries suggests they are safe.

In summary, hydrocolloid dressings like DuoDERM EXTRA THIN are considered safe for wound care and offer a promising alternative to traditional treatments. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about hydrocolloid dressings for facial reconstruction because they offer a unique approach to wound healing. Unlike traditional treatments that often rely on antibiotic ointments to prevent infection, hydrocolloid dressings create a moist environment that promotes faster healing and reduces scarring. This innovative method not only protects the wound from contaminants but also allows the body’s natural healing processes to work more efficiently. The potential for reduced recovery time and improved cosmetic outcomes makes this treatment particularly promising for facial surgeries.

What evidence suggests that hydrocolloid dressings are effective for facial reconstruction?

Research has shown that hydrocolloid dressings can improve wound healing and reduce scarring after facial surgeries. In this trial, some participants will receive hydrocolloid dressings, which have been found to promote faster healing and are easier to use than traditional methods. Studies indicate that these dressings simplify and enhance post-surgery care. They may also improve scar appearance, a crucial factor in facial surgeries. Overall, hydrocolloid dressings appear to be a promising alternative to antibiotic ointments, used in the control arm of this trial, for post-surgery wound care. ^{1 3 6 7 8}

Who Is on the Research Team?

Janice Hernandez, MD

Principal Investigator

University of Kentucky

Are You a Good Fit for This Trial?

This trial is for individuals who have undergone facial reconstruction or Mohs surgery and are in the process of wound healing. Participants should be suitable candidates for the use of hydrocolloid dressings post-surgery.

Inclusion Criteria

I am over 18 years old.

My eligibility is not affected by my gender, ethnicity, or religion.

Patients must be able to give informed consent

Exclusion Criteria

I am between 18 and 100 years old.

History of allergy to pectin, gelatin, and sodium carboxymethylcellulose

Incarcerated individuals

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either a hydrocolloid dressing or antibiotic ointment immediately after surgery, with the dressing removed at a post-operative week 1 appointment

1 week

1 visit (in-person)

Follow-up

Participants are monitored for wound healing and scar assessment over a 3-month period

3 months

What Are the Treatments Tested in This Trial?

Interventions

• Hydrocolloid Dressings

Trial Overview The study tests a hydrocolloid dressing, DuoDERM EXTRA THIN, as an alternative to standard care after facial reconstructive surgery. It's applied immediately post-op and evaluated at a week 1 follow-up visit, aiming to simplify patient care.

How Is the Trial Designed?

Group I: Wound Dressing Experimental Treatment 1 Intervention

At the conclusion of the surgical procedure, patients will receive topical wound dressing to surgical sutured periocular wounds

Group II: Antibiotic Ointment (Control) Active Control 1 Intervention

At the conclusion of the surgical procedure, patients will receive topical antibiotic ophthalmic ointment to surgical sutured periocular wounds

Who Is Running the Clinical Trial?

Janice Hernandez, MD

Lead Sponsor

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10883250/

Role of hydrocolloid dressing in preventing face pressure ... In maxillofacial surgery, patients treated with hydrocolloid dressings exhibited improved wound healing and reduced scar formation, evidenced by ...

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11856799/

Narrative Review of the Use of Hydrocolloids in Dermatology Hydrocolloid dressings appear to be an effective treatment in acute wounds, with the potential of reduced healing time and easier application compared to ...

3. jaadinternational.org jaadinternational.org/article/S2666-3287(21)00090-0/fulltext

Hydrocolloid dressing versus conventional wound care ... A simplified wound care regimen involving HCD can potentially lead to increased comfort, convenience, simplicity, and a subjective improvement in scar ...

4. patlynk.com patlynk.com/trial/NCT07075159

Hydrocolloid Dressings for Oculofacial Wound Healing This study seeks to find out if using this dressing can replace the ointment and simplify post-operative care, making recovery easier for patients. In this ...

5. academic.oup.com academic.oup.com/milmed/article/189/11-12/e2523/7678860

Impact of Hydrocolloid Dressing and Moisturizing Cream as ... We assessed the use of hydrocolloid dressing versus dimethicone cream to prevent skin breakdown among military health care workers while wearing an N95.

6. clinicaltrials.gov clinicaltrials.gov/study/NCT07075159

Study Details | NCT07075159 | Hydrocolloid Dressings for ... This study aims to explore the use of a hydrocolloid dressing (DuoDERM EXTRA THIN) as an alternative to the current standard of care. The dressing would be ...

7. withpower.com withpower.com/trial/phase-oculofacial-reconstruction-6-2025-89bf1

Hydrocolloid Dressings for Facial Reconstruction ... Dressings will have tolerable side effects & efficacy for patients with Facial Reconstruction, Wound Healing and Mohs Surgery. See if you qualify today!

8. sciencedirect.com sciencedirect.com/science/article/pii/S2666328721000900

Hydrocolloid dressing versus conventional wound care ... Objective. To examine whether a one-time HCD application after dermatologic surgery results in greater patient satisfaction and improved postoperative outcomes ...