Ocular Ultrasound for Optic Nerve Assessment

Overseen By Jessica Krizo, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Akron General Medical Center

Disqualifiers: Acute ocular pathology, Abnormal CT, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: 15-20 minutes

30 Participants Needed

Trial Summary

What is the purpose of this trial?

This study is a prospective assessment of the accuracy of ocular ultrasound as a tool to measure the diameter of the optic nerve sheath and the eyeball transverse diameter in healthy adult patients presenting to the Emergency Department and have confirmatory imaging of the optic nerve as part of their clinical care.

Research Team

Joshua Jacquet, MD

Principal Investigator

Cleveland Clinic Akron General

Eligibility Criteria

This trial is for adults over 18 who visit the Cleveland Clinic Akron General's ED, need a CT scan of their head or eyes as part of normal care, and can give written consent. It's not for pregnant or incarcerated individuals, those with eye diseases, abnormal brain/eye CTs, unstable health conditions, or past issues with high pressure in the brain.

Inclusion Criteria

Agree to and provide written consent for participation

My recent head or eye scans show no signs of acute illness.

Present to Cleveland Clinic Akron General's ED (Main)

Exclusion Criteria

Not medically stable

Abnormal brain and/or ocular CT

Pregnant or incarcerated

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo ocular ultrasound with two different probes for a total of four ultrasounds

15-20 minutes

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 year

Treatment Details

Interventions

• Ocular Ultrasound

Trial Overview The study is testing how well ocular ultrasound works to measure optic nerve sheath diameter in healthy patients. Participants will have this non-invasive test alongside standard imaging procedures during their emergency department visit.

Participant Groups

Group I: Ocular Ultrasound Experimental Treatment 1 Intervention

This arm includes all patients enrolled who will have an ocular ultrasound with two different probes for a total of four ultrasounds.

Who Is Running the Clinical Trial?

Akron General Medical Center

Lead Sponsor

Trials

7

Recruited

280+

Cleveland Clinic Akron General

Lead Sponsor

Trials

8

Recruited

480+