Engaging Visual Field Test for Pediatric Eye Examinations

Recruiting at 1 trial location

Overseen By So Yeon Lee, OD

Age: < 18

Sex: Any

Trial Phase: Academic

Sponsor: Nova Southeastern University

Disqualifiers: Previous VF test, Cognitive impairment, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

Duration: 1 week

20 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to make eye tests more fun and engaging for kids, potentially improving the accuracy of diagnosing vision problems. Researchers are testing a new method to check peripheral vision using cartoons and fun voices to maintain children's focus. This approach, called the "Cartoon video fixation target and cartoon character voice audio instructions during Humphrey perimetry," could enhance test results and enable earlier detection of vision issues. Children aged 5 to 8 who have visited Nova Southeastern University for suspected glaucoma or optic nerve issues might be suitable candidates. The trial involves two visits to compare this new method with standard eye tests. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could make eye tests more enjoyable and effective for children.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this device is safe for pediatric eye examinations?

Research has shown that using cartoon videos and character voices during eye tests is safe for children. This method makes the test more enjoyable, helping kids pay better attention. Studies have found this approach to be harmless and popular with children. The setup includes a small screen displaying cartoons and audio instructions, which keeps kids entertained and focused, enhancing the reliability of test results. So far, no negative effects have been reported from using this enjoyable and creative method during eye exams. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about this trial because it could make eye exams more engaging for children. Unlike standard procedures that can be dull and hard for kids to focus on, this trial uses cartoon videos and character voices to capture their attention during visual field tests. This innovative approach aims to improve the accuracy of test results by keeping young patients interested and cooperative. If successful, it might transform how pediatric eye exams are conducted, making them more effective and child-friendly.

What evidence suggests that this device is effective for improving visual field test reliability in children?

This trial will compare the use of cartoon videos and voices during eye tests with usual care procedures for young children. Research has shown that cartoon videos and voices can make the experience more enjoyable, helping children pay better attention and remain consistent during the test. Studies have found that increased focus in children leads to more reliable test results. This improved reliability can enhance diagnosis and care for children with vision problems. The aim is to create an enjoyable and effective test environment, potentially detecting eye issues earlier and more accurately. ^{1 2 3 5 6}

Who Is on the Research Team?

Ava Bittner

Principal Investigator

University of California, Los Angeles

Are You a Good Fit for This Trial?

This trial is for children aged 5-8 who can complete vision tests and have been seen at Nova Southeastern University's The Eye Care Institute for possible glaucoma or optic nerve issues. They must understand English well and be able to communicate their responses.

Inclusion Criteria

Provide informed consent

I have been seen at Nova Southeastern University for possible glaucoma or optic nerve issues.

I can attend 2 study visits a week apart for vision field tests.

Exclusion Criteria

I can understand and communicate about the study.

You have completed a visual field test using Humphrey static perimetry before.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo visual field testing using either the cartoon intervention or usual care procedures

1 week

2 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

What Are the Treatments Tested in This Trial?

Interventions

• Cartoon video fixation target and cartoon character voice audio instructions during Humphrey perimetry

Trial Overview The study is testing a new way to do vision tests using cartoon videos and character voices as instructions, hoping it will keep kids' attention better than the usual method. This could make the test results more reliable.

How Is the Trial Designed?

Group I: Cartoon Intervention Experimental Treatment 1 Intervention

Cartoon video fixation target and cartoon character voice audio instructions during Humphrey perimetry

Group II: Usual Care Active Control 1 Intervention

Usual care procedures for Humphrey perimetry in young children

Who Is Running the Clinical Trial?

Nova Southeastern University

Lead Sponsor

Trials

103

Recruited

12,000+

Published Research Related to This Trial

A gamified approach to assessing Contrast Sensitivity Function (CSF) in children with amblyopia was tested on 25 participants aged 4 to 9 years, showing that the method was engaging and easy for young children to understand and complete.

The new testing method effectively distinguished between varying degrees of amblyopia and was able to separate affected eyes from healthy ones, suggesting it could be a practical tool for pediatric vision assessments in various settings.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Can Psychophysics Be Fun? Exploring the Feasibility of a Gamified Contrast Sensitivity Function Measure in Amblyopic Children Aged 4-9 Years. Elfadaly, D., Abdelrazik, ST., Thomas, PBM., et al.[2020]

A new head-mounted VR display with gaze-contingent flicker pupil perimetry (VRgcFPP) was tested on 20 children aged 3-11 years, showing it effectively measures visual field responses while allowing children to move freely and engage with the task.

The fixation counting task was found to be the most effective method for eliciting strong pupil responses, as children enjoyed it the most, indicating it could be the best practice for assessing visual fields in young children.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Maintaining fixation by children in a virtual reality version of pupil perimetry. Portengen, BL., Naber, M., Jansen, D., et al.[2023]

A novel computer game-based system was successfully developed to measure visual fields in children, tested on 25 eyes of 19 children aged 4-14 years, demonstrating its feasibility as a non-invasive and engaging method.

The system effectively identified normal and abnormal visual fields, with positive feedback from children, indicating that it could be a valuable tool for pediatric eye assessments.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A novel paediatric game-based visual-fields assessor. Aslam, TM., Rahman, W., Henson, D., et al.[2022]

Automated static perimetry can be reliably performed in children aged 8 years and older, with good reproducibility in those aged 13 and above, indicating its feasibility in clinical settings.

Continuous light increment perimetry (CLIP) was found to be more effective than the fast threshold strategy (FT), showing fewer abnormal results and false positives, especially beneficial for younger children.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Feasibility and outcome of automated static perimetry in children using continuous light increment perimetry (CLIP) and fast threshold strategy. Wabbels, BK., Wilscher, S.[2022]

A new pediatric visual field test using a computer game was developed and tested on 20 children aged 4-16, showing that it is a feasible and enjoyable method for assessing visual fields in kids.

While the game-based test produced sensitivity values similar to those of adults, the variability in results was high, indicating that further refinement may be needed to improve consistency in measurements.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Development of a Pediatric Visual Field Test. Miranda, MA., Henson, DB., Fenerty, C., et al.[2022]

Patients who received audiovisual instructions via a video showed better performance and motivation during automated Humphrey visual field testing compared to those who received verbal instructions, with 85% of the video group finding the instructions helpful.

The video-instructed group had a higher reliability in test results (47.5%) and reported feeling more confident and less anxious, suggesting that audiovisual aids can enhance patient understanding and performance in medical testing.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Comparison of the effect of audiovisual and verbal instructions on patient performance while performing automated Humphrey visual field testing. Maheshwari, D., Nair, A., Tara, TD., et al.[2023]

The Olleyes VisuALL-K, a pediatric virtual reality perimetry device, demonstrated comparable threshold sensitivity to the traditional Humphrey Field Analyzer (HFA) in mapping peripheral vision in children, with mean sensitivities of 31.8 dB for VRP and 31.0 dB for HFA.

Despite a longer testing time of 7.6 minutes for VRP compared to 5.3 minutes for HFA, children reported higher satisfaction with the VRP, indicating its potential as a more engaging and flexible option for vision testing in pediatric patients.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Evaluation of Virtual Reality Perimetry and Standard Automated Perimetry in Normal Children. Groth, SL., Linton, EF., Brown, EN., et al.[2023]

Citations

1. withpower.com withpower.com/trial/phase-ocular-hypertension-1-2015-b5e81

Engaging Visual Field Test for Pediatric Eye Examinations This approach, called the "Cartoon video fixation target and cartoon character voice audio instructions during Humphrey perimetry," could enhance test results ...

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10115433/

Maintaining fixation by children in a virtual reality version of ... The VR set-up appears to be an ideal apparatus for children to allow free range of movement, an engaging visual task, and reliable eye measurements.

3. researchgate.net researchgate.net/publication/364310215_Maintaining_fixation_by_children_in_a_virtual_reality_version_of_pupil_perimetry

(PDF) Maintaining fixation by children in a virtual reality ... The results showed that gaze precision and accuracy did not differ significantly across the fixation conditions but pupil amplitudes were ...

4. iovs.arvojournals.org iovs.arvojournals.org/article.aspx?articleid=2563317

A More Engaging Visual Field Test to Increase Use and ... - IOVS The intervention includes a 1.5” micro-display video screen displaying popular cartoon characters as the fixation target and audio clips of an impersonated ...

5. clinicaltrial.be clinicaltrial.be/nl/details/74755?only_active=0&only_eligible=0&only_recruiting=0&per_page=100

A More Engaging Visual Field Test to Increase Use and Rel... Improved VF reliability from the investigators intervention would translate to improved diagnosis and care for young childrens' peripheral vision loss through ...

6. youtube.com youtube.com/watch?v=oY7mJAGMOkM

Humphrey Visual Field (HVF) Test at Alexandra Hospital The Humphrey Visual Field (HVF) is a test performed to measure the quality of your visual field. It measures how wide and sensitive your ...