Exercise for Obesity

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Virginia, Charlottesville, VAObesity+2 MoreExercise - Other
Eligibility
40 - 55
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing the impact of exercise intensity on the hormone ghrelin, as well as how changes in ghrelin from exercise affect obesity, insulin sensitivity, and vascular function.

Eligible Conditions
  • Obesity
  • Insulin Resistance
  • Cardiovascular Risk

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: Insulin and glucose will be collected at 5 timepoints during the OGTT, and 11 timepoints during each testing visit. The Matsuda index (mathematical model) will be used to calculate insulin sensitivity

Body composition will be measured twice during a DEXA and CT scan (takes about 30 minutes)
Body Composition
Insulin and glucose will be collected at 5 timepoints during the OGTT, and 11 timepoints during each testing visit. The Matsuda index (mathematical model) will be used to calculate insulin sensitivity
Insulin Sensitivity
Hour 3
Vascular Function (brachial flow mediated dilation)
Hour 3
Appetite Questionnaire (VAS)
Ghrelin

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

Control
1 of 3
Moderate Intensity Exercise
1 of 3
High Intensity Exercise
1 of 3

Active Control

Experimental Treatment

80 Total Participants · 3 Treatment Groups

Primary Treatment: Exercise · No Placebo Group · N/A

Moderate Intensity Exercise
Other
Experimental Group · 1 Intervention: Exercise · Intervention Types: Other
High Intensity Exercise
Other
Experimental Group · 1 Intervention: Exercise · Intervention Types: Other
ControlNoIntervention Group · 1 Intervention: Control · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: insulin and glucose will be collected at 5 timepoints during the ogtt, and 11 timepoints during each testing visit. the matsuda index (mathematical model) will be used to calculate insulin sensitivity

Who is running the clinical trial?

University of VirginiaLead Sponsor
694 Previous Clinical Trials
1,467,401 Total Patients Enrolled
15 Trials studying Obesity
1,382 Patients Enrolled for Obesity
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,182 Previous Clinical Trials
4,088,817 Total Patients Enrolled
412 Trials studying Obesity
493,801 Patients Enrolled for Obesity

Eligibility Criteria

Age 40 - 55 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are between 40 and 52 years old.
You exercise less than two days per week.
Your body mass index (BMI) is between 18 to 35.

Frequently Asked Questions

Is enrollment in this medical trial open to individuals aged twenty-five or older?

"This medical study seeks patients aged 40 to 55 for its clinical trial. Additionally, there are 220 trials that admit applicants below 18 years of age and 725 studies open to people 65 or older." - Anonymous Online Contributor

Unverified Answer

Is enrollment for this trial still open?

"As shown on the clinicaltrials.gov website, this trial is still actively recruiting participants who are willing to take part in it. This research project was initially posted on October 14th 2020 and underwent its most recent update on May 13th 2022." - Anonymous Online Contributor

Unverified Answer

Do I fulfill the qualifications for participation in this clinical experimentation?

"This medical trial has a target of 80 participants who must be between 40 and 55 years old, with insulin resistance as the primary qualification." - Anonymous Online Contributor

Unverified Answer

How many people have signed up to partake in this research?

"Affirmative. The information on clinicaltrials.gov affirms that this research is currently accepting participants. This study was unveiled on October 14th 2020 and the latest update was made on May 13th 2022, with a requirement of 80 patients across 1 medical facility." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.