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Individuals with normal BMI for Obesity

N/A
Waitlist Available
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30-60 minutes
Awards & highlights

Study Summary

This trial will compare sympathetic nervous system activity in obese and non-obese people. It will look at how different genders affect this activity, and how this activity changes before and after a high carbohydrate meal.

Eligible Conditions
  • Obesity
  • Healthy Subjects

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30-60 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30-60 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Distribution Volume Ratio (DVR) of [11C]MRB PET Imaging of Peripheral Sympathetic Nervous System
Microneurography (Muscle Sympathetic Nerve Activity (MSNA)) Measured by Burst Frequency
Secondary outcome measures
C-Peptide
DVR of Norepinephrine Transporter (NET) in the Central Nervous System (CNS)
DVR of [11C]MRB PET Imaging of Peripheral Sympathetic Nervous System After Mixed Meal Test
+7 more

Trial Design

2Treatment groups
Active Control
Group I: Individuals with normal BMIActive Control7 Interventions
(BMI 18-25 kg/m2)
Group II: Individuals with obesityActive Control7 Interventions
(BMI 30-40 kg/m2)

Find a Location

Who is running the clinical trial?

Yale UniversityLead Sponsor
1,847 Previous Clinical Trials
2,737,663 Total Patients Enrolled
59 Trials studying Obesity
248,143 Patients Enrolled for Obesity
National Institutes of Health (NIH)NIH
2,696 Previous Clinical Trials
6,952,574 Total Patients Enrolled
103 Trials studying Obesity
25,851 Patients Enrolled for Obesity

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Sympathetic Activation in Obesity
2021. "Sympathetic Activation in Obesity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04946552.
~1 spots leftby Apr 2025
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