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Normal-weight obesity for Obesity

N/A
Recruiting
Research Sponsored by Oklahoma State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up approximately 8 months
Awards & highlights

Study Summary

This trial will examine how exercise affects gut permeability & inflammation in people at risk for CVD, like those with normal-weight obesity.

Eligible Conditions
  • Obesity
  • Normal-weight Obesity

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately 8 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 8 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Serum concentrations of FABP2 following short, intense exercise
Serum concentrations of FABP2 following sustained, moderate exercise
Serum concentrations of IL-6 following sustained, moderate exercise
+2 more
Secondary outcome measures
Heart rate dynamics during exercise sessions
Maximum workload during exercise sessions
Respiratory exchange ratio (RER) during VO2 max test
+1 more
Other outcome measures
Absolute body fat assessment with dual-energy X-ray absorptiometry (DXA)
Absolute lean mass assessment with dual-energy X-ray absorptiometry (DXA)
Absolute visceral fat mass assessment with dual-energy X-ray absorptiometry (DXA)
+3 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Normal-weight obesityExperimental Treatment1 Intervention
Individuals with normal-weight obesity will be defined as having normal BMI (18.5 - 24.9 kg/m2), body fat percent > 25% (male) or > 35% (female).
Group II: Overt obesity and high body fat percentActive Control1 Intervention
Overt obesity (BMI > 30 kg/m2) with high body fat percent (> 25% [male] or > 35% [female]) will be used as a high-risk comparator group.
Group III: Normal weight and low body fat percentActive Control1 Intervention
The low risk comparator group for this study will consist of individuals with normal BMI (18.5 - 24.9 kg/m2) and body fat percent < 25% (male) or < 35% (female).

Find a Location

Who is running the clinical trial?

Oklahoma State UniversityLead Sponsor
46 Previous Clinical Trials
8,242 Total Patients Enrolled
5 Trials studying Obesity
389 Patients Enrolled for Obesity

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What type of individuals is the ideal candidate for this clinical research?

"A prerequisite for potential participants in this study is obesity and they must be between 18-50 years of age. 30 individuals are sought out to participate in the trial."

Answered by AI

Is there an upper age limit for enrollment in this clinical research program?

"To be included in this trial, participants must fall within the 18 to 50 year old age bracket. Alternatively, there are 221 trials that cater for younger adults and 656 clinical studies targeting elderly patients."

Answered by AI

Is enrollment for this investigation still available?

"As of the latest update, clinicaltrials.gov reports that this medical trial is still actively recruiting participants. The initial post date was January 10th 2023 and the report has been edited most recently on June 2nd 2023."

Answered by AI

How many participants are involved in the current clinical trial?

"Affirmative, clinicaltrials.gov hosts data that reveals the recruitment phase of this trial is still active. It was published on January 10th 2023 and most recently revised on June 2nd 2023; 30 people are required to participate across a single medical centre."

Answered by AI

Could you explain the main aims of this trial?

"During this 8-month trial, the primary outcome to be measured is serum concentrations of LBP following short and intense exercise. Secondary outcomes include RER dynamics during VO2 max test, maximum workloads in watts for both types of exercises, and heart rate fluctuations throughout each session."

Answered by AI

Who else is applying?

What state do they live in?
Kansas
What site did they apply to?
208 Nancy Randolph Davis, Oklahoma State University
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

The older I get the harder it is to lose weight and easier to gain. I've always been a 135-150.
PatientReceived no prior treatments

What questions have other patients asked about this trial?

How long do the screenings take?
PatientReceived no prior treatments
Recent research and studies
clinicaltrials.govStudy
Exercise-Induced Gut Permeability in Normal-weight Obesity
Sam Emerson 2023. "Exercise-Induced Gut Permeability in Normal-weight Obesity". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05889767.
~13 spots leftby Apr 2025
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