400 Participants Needed

Genomic Testing for Advanced Cancer

(BEGIN Trial)

Recruiting at 6 trial locations
JB
ZS
RC
Overseen ByRheanna Carter, MBA
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: BostonGene
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to evaluate the effectiveness of detailed molecular testing for individuals with advanced cancer. It employs the BostonGene Tumor Portrait test to enhance treatment decisions by identifying specific cancer traits. Patients with certain hard-to-treat cancers, such as advanced breast cancer, lung cancer, melanoma, or sarcoma, may be suitable candidates. The goal is to demonstrate how this testing can guide therapy and improve outcomes in everyday healthcare settings. As a Phase 2 trial, this research measures the treatment's effectiveness in an initial, smaller group, providing participants an opportunity to contribute to groundbreaking advancements in cancer care.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

The BostonGene and Exigent Genomic INsight Study is unique because it explores cutting-edge genomic insights to tailor cancer treatment more precisely than ever before. Unlike traditional cancer treatments that often involve a one-size-fits-all approach, this study focuses on personalizing therapy based on the genetic makeup of a patient’s tumor. Researchers are excited about this trial because it has the potential to revolutionize how we approach cancer treatment, offering more effective and targeted options with potentially fewer side effects. By understanding the specific genetic drivers of a person's cancer, this approach could lead to better outcomes and a more personalized treatment experience.

Are You a Good Fit for This Trial?

Inclusion Criteria

My cancer is advanced and cannot be removed by surgery.
My doctor expects me to live more than 3 months.
I agree to have my cancer's genes tested.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Molecular Testing

Participants undergo comprehensive molecular testing using the BostonGene Tumor Portrait test to identify actionable findings

2 years

Treatment Decision

Treatment decisions are made based on the results of the molecular testing, focusing on molecularly matched therapies

12 months

Follow-up

Participants are monitored for safety and effectiveness after treatment decisions are made

12 months

What Are the Treatments Tested in This Trial?

Interventions

  • BostonGene Tumor Portrait test

Find a Clinic Near You

Who Is Running the Clinical Trial?

BostonGene

Lead Sponsor

Trials
2
Recruited
100,000+

Exigent

Collaborator

Trials
1
Recruited
400+

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