1050 Participants Needed

Registry for Peripheral Nerve Sheath Tumor

Recruiting at 8 trial locations
AH
Overseen ByAngela Hirbe, M.D., Ph.D.
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Washington University School of Medicine
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to better understand malignant peripheral nerve sheath tumors, a rare cancer often linked to neurofibromatosis type 1 (NF1). Researchers are establishing a global database to gather information about these tumors from various medical centers. The goal is to uncover patterns that could lead to more effective treatments. Individuals diagnosed with these tumors can participate if they agree to have their tumor samples and related data collected for study. As an unphased trial, participation offers a unique opportunity to contribute to groundbreaking research that could shape future treatments.

Why are researchers excited about this trial?

Unlike the standard treatments for malignant peripheral nerve sheath tumors, which often involve surgery, radiation, and chemotherapy, this clinical trial is focused on creating a comprehensive registry. Researchers are excited about this trial because it aims to gather extensive data from multiple institutions, which can lead to a better understanding of these rare tumors. By analyzing this data, researchers hope to uncover patterns and insights that could pave the way for more targeted and effective therapies in the future.

Who Is on the Research Team?

AH

Angela Hirbe, M.D., Ph.D.

Principal Investigator

Washington University School of Medicine

Are You a Good Fit for This Trial?

Inclusion Criteria

Inclusion Criteria

Timeline for a Trial Participant

Retrospective Analysis

A retrospective analysis to determine the clinical landscape of NF1-associated MPNST and precursor lesions

10 years

Prospective Sample Collection

Prospective collection of MPNST samples for analysis and genomic characterization

10 years

Follow-up

Participants are monitored for safety and effectiveness after treatment

10 years

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

Washington University School of Medicine

Lead Sponsor

Trials
2,027
Recruited
2,353,000+

Boston's Children Hospital

Collaborator

Trials
1
Recruited
1,100+
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