RELVAR for COPD
What You Need to Know Before You Apply
What is the purpose of this trial?
This study examines the effect of the ultra long acting beta agonist/corticosteroid bronchodilator combination fluticasone furoate/vilanterol trifenatate, on respiratory muscles and ventilation in adults with severe bronchitis or emphysema (COPD).
Do I need to stop my current medications for the trial?
The trial does not specify if you need to stop your current medications, but it requires participants to be on long-acting bronchodilator therapy. It's best to discuss your current medications with the trial team.
Is RELVAR safe for humans?
How is the drug Fluticasone Furoate/Vilanterol unique for treating COPD?
Fluticasone Furoate/Vilanterol is unique because it combines a corticosteroid with a long-acting bronchodilator in a once-daily inhaler, which can improve lung function and reduce flare-ups more effectively than some other treatments. Its once-daily dosing may also help patients stick to their treatment plan better.12367
What data supports the effectiveness of the drug RELVAR for COPD?
Who Is on the Research Team?
Paul A Easton, MD, PhD
Principal Investigator
University of Calgary
Are You a Good Fit for This Trial?
This trial is for adults with severe COPD who can handle a minor surgery with sedation, take their meds regularly, and are able to walk. They should be on long-term bronchodilator therapy but not have had a major flare-up in the last 2 months or serious heart issues.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive inhalation of fluticasone furoate/vilanterol trifenatate, 100 mcg/25 mcg combination, using a standard dry powder inhaler
Follow-up
Participants are monitored for changes in minute ventilation, parasternal EMG, and pressure with phrenic stimulation after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Fluticasone Furoate
- Vilanterol Trifenatate
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Calgary
Lead Sponsor