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Radiation Therapy

Kypho-IORT for Spinal Metastases (Kypho-IORT Trial)

N/A
Waitlist Available
Led By Maged Ghaly, MD
Research Sponsored by Northwell Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Kypho-IORT Trial Summary

This trial is studying a novel approach to treating spinal cord metastases that involves a minimally invasive procedure called kyphoplasty, combined with a single dose of intraoperative radiotherapy (IORT). The primary objective is to evaluate the response rate of pain control, while secondary objectives are to determine feasibility and tolerability/side effects of the IORT, as well as to identify clinical factors that are prognostic of vertebral compression fracture.

Eligible Conditions
  • Spinal Metastases

Kypho-IORT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
To evaluate pain control
Secondary outcome measures
Feasibility of Kypho-IORT as treatment modality
Local tumor control
Measures of quality of life.
+3 more

Kypho-IORT Trial Design

1Treatment groups
Experimental Treatment
Group I: KYPHO-IORT - 10 Gy and KyphoplastyExperimental Treatment1 Intervention
Intra-operative radiation therapy followed by standard kyphoplasty
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Kypho-IORT
2016
N/A
~30

Find a Location

Who is running the clinical trial?

Northwell HealthLead Sponsor
459 Previous Clinical Trials
470,951 Total Patients Enrolled
Maged Ghaly, MD3.68 ReviewsPrincipal Investigator - Northwell Health
Northwell Health
1 Previous Clinical Trials
39 Total Patients Enrolled
5Patient Review
Dr. Ghaly is excellent! One of the best doctors I've ever met. He took time to explain everything in detail. I had extreme anxiety about the procedure, but felt comfortable with Dr. Ghaly- he has that rare combination of technical brilliance plus warm personality- kind & caring, w a good sense of humor. He held my hand during part of the procedure when I was freaking out & focused on me to assess for distress, then took appropriate action to fix- I would say he has a very high level of empathy.

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Kypho-Intra Operative Radiation Therapy (IORT) for Localized Spine Metastasis, Phase I/II Study
Maged Ghaly 2016. "Kypho-Intra Operative Radiation Therapy (IORT) for Localized Spine Metastasis, Phase I/II Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02987153.
~3 spots leftby Apr 2025
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