This trial is evaluating whether Tailored Exercise Intervention will improve 11 primary outcomes and 15 secondary outcomes in patients with Brain Cancer. Measurement will happen over the course of At baseline (0 weeks)..
This trial requires 100 total participants across 2 different treatment groups
This trial involves 2 different treatments. Tailored Exercise Intervention is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
There are few treatments, when compared to other cancers, that are effective for all types of [brain cancer](https://www.withpower.com/clinical-trials/brain-cancer). These include surgery, radiation therapy, chemotherapy, and targeted therapy. There are many different types of brain cancer and each cancer must be treated based on specific characteristics. Many neurosurgeons participate in research on ways to develop effective brain cancer treatments.\n\nThe first step is to understand the symptoms and signs of a brain tumour by performing a complete neurological examination. Imaging usually reveals a mass on a CT scan or MRI scan.\nTo determine prognosis from the brain tumour data, the doctor will examine a patient along with the patient's general health, history of medical treatments, and any side effects.
The most common signs of brain cancer are headache and loss of balance. Symptoms can be very vague and can manifest in a variety of different ways. This is why it is important to understand and document the symptoms as many other signs of brain cancer can make initial presentation difficult to recognize and report. If symptoms become worse or more frequent or both, they should be referred to the GP for further assessment. There are no screening tests or signs to help rule out brain cancer.\n
Cancer of the brain and CNS is a multi-faceted malignancy and is an ever-increasing medical problem. Most cases are related to primary [brain cancer](https://www.withpower.com/clinical-trials/brain-cancer), the result of a metastatic process initiated in a distant site. Brain metastasis is the leading cause of mortality in patients with cancer. The brain contains an abundance of blood vessels and so its metastasis is one of the most lethal of all cancers. Neuroimaging techniques are now increasingly used to find and visualize lesions of primary brain cancer.
Brain cancer begins before or during pregnancy, and can be associated with a history of radiation exposure. The risk of brain cancer is also affected by genes and the environment. Current research needs to focus on elucidating the links between factors that increase brain cancer and those that reduce the risk of brain cancer. If these risk factors can be identified, then, we would have a more rational approach for screening programs.
Although a number of strategies are in use to minimize the consequences of metastatic cancer, the prevention of new diagnoses and cancer related deaths would remain an incredibly challenging task for those whose only option is active treatment, particularly when other treatment options are ineffective or unavailable.
The present study showed an overall [brain cancer](https://www.withpower.com/clinical-trials/brain-cancer) incidence of 1.4 per 100,000 persons, much lower than those from studies using other screening systems, which suggest a rate approaching 2 per 100,000.[reference needed] The present study's result was based on the premise that all patients with brain tumor must undergo brain examination because only those patients would have their tumor diagnosed. Another study that included patients without brain tumors of any kind showed that the incidence of brain cancer was 5.5 per 100,000.
The exercise intervention reduced fatigue, increased participation in leisure time exercise, and improved QOL. Tailored exercise interventions should be explored as an effective means of reducing fatigue, improving QOL and maintaining participation in leisure activity for persons with BCTs.
The risk of developing [brain cancer](https://www.withpower.com/clinical-trials/brain-cancer) is approximately 1.5 per 1,000 and increases during adulthood. This risk varies significantly by race and ethnicity, gender, socioeconomic status and access to healthcare systems.
Tailored exercise intervention is an effective strategy for the control of risk factors and disease burden in breast cancer survivors, particularly if the intervention is high-intensity, progressive, and supervised.
We can say that the search for new treatments for brain cancer will continue. At the start of the 20th century we had no cures for these tumours. In the last decade several new effective drugs have been introduced for treating some types of brain tumours. For example, gefitinib, pazopanib, or erlotinib, which inhibits a protein that is essential for tumour cell growth have proven to be useful agents in cases where the mutant EGFR gene is present.
The trial was run to a standard research protocol in an environment supportive of evidence-based practice. The study complied with Good Clinical Practice guidelines. Given this, the findings of the current study will be discussed in light of current evidence regarding exercise intervention for cancer survivors.
Current research on physiotherapy interventions may be of benefit, but current findings are limited in terms of knowledge transfer from research to practice, and the need for high quality research to examine best practice approaches to exercise intervention in patients with neurological conditions. A better way to progress in this field is to coordinate research on physiotherapy interventions.