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Medication Optimization for Anxiety

N/A

Waitlist Available

Led By Michael Avidan, MBBCh, FCASA

Research Sponsored by Washington University School of Medicine

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 1 month, and 3 months

Awards & highlights

Study Summary

This trial will test whether a mental health intervention bundle can help improve outcomes for older surgical patients. The bundle includes behavioral activation and medication optimization.

Eligible Conditions

Aging Adults
Anxiety
Depression
Cardiac Surgery
Orthopedic Procedures
Thoracic Surgery
Abdominal Cancer Surgery

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 1 month, and 3 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 1 month, and 3 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1 month, and 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Reach of the Intervention Bundle as Measured by the Number of Participants Who Completed the Intervention Out of the Participants Who Agreed to Participate in the Study

Reach of the Study as Measured by the Number of Participants Who Agree to Participate in the Study Out of the Total Eligible Participants

Secondary outcome measures

Completeness of Planned Data Collection at Specified Timepoints as Measured by the Number of Participants Who Completed 100% of the Patient Health Questionnaire Anxiety and Depression Scale (PHQ-ADS)

Trial Design

1Treatment groups

Experimental Treatment

Group I: Patient ParticipantsExperimental Treatment2 Interventions

Behavioral activation (BA) will span across 3 months postoperatively & will begin pre-operatively, with sessions approximately weekly or biweekly, depending on patient preference & health condition. Medications will be reviewed & optimized by a team of interventionists including a psychiatrist, pharmacologist, & pharmacists. While the participant is in-hospital, the interventionist's role will include coordinating with the hospital team to ensure that medication changes that were introduced preoperatively are maintained in-house & that no new inappropriate medications are initiated. After discharge, & up to approximately 3 months postoperatively, the interventionist will ensure that medication changes are reconciled during transitions of care. The interventionists will ensure the agreed-upon changes are implemented, or an alternative course of action is justified.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Behavioral Activation

2013

Completed Phase 3

~2980

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Find a Location

Who is running the clinical trial?

Washington University School of MedicineLead Sponsor

1,931 Previous Clinical Trials

2,299,685 Total Patients Enrolled

12 Trials studying Anxiety

1,748 Patients Enrolled for Anxiety

National Institute of Mental Health (NIMH)NIH

2,782 Previous Clinical Trials

2,689,083 Total Patients Enrolled

82 Trials studying Anxiety

39,076 Patients Enrolled for Anxiety

Michael Avidan, MBBCh, FCASAPrincipal InvestigatorWashington University School of Medicine

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is participation in this experiment still available to the public?

"Affirmative, the information on clinicaltrials.gov confirms that this trial is presently recruiting participants. Originally posted on November 17th 2021 and recently revised on July 12 2022, 70 individuals will be sought from a single region for participation in this research project."

Answered by AI

To what extent has the patient participant pool grown in this clinical experiment?

"Affirmative, the clinical trial is recruiting patients. According to data hosted on clinicaltrials.gov, this study was first published in November 17th 2021 and has since been adjusted up until July 12th 2022. 70 participants are sought for recruitment at a single location."

Answered by AI