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Diagnostic Procedure

Dynamic Susceptibility Contrast-MRI (DSC-MRI) for Brain Metastasis

N/A
Waitlist Available
Led By Hui-Kuo Shu, MD, PhD
Research Sponsored by Emory University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline up to 1 year
Awards & highlights

Study Summary

This trial is testing whether using MRI to look for changes after radiation therapy can help determine if the changes are due to the cancer growing or to other side effects of the radiation.

Eligible Conditions
  • Brain Metastasis
  • Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline up to 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline up to 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in dynamic susceptibility contrast (DSC)-magnetic resonance imaging (MRI) parameters: mean transit time (MTT)
Change in dynamic susceptibility contrast (DSC)-magnetic resonance imaging (MRI) parameters: percentage of signal intensity recovery (PSR)
Change in dynamic susceptibility contrast (DSC)-magnetic resonance imaging (MRI) parameters: relative cerebral blood volume (rCBV)
+1 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diagnostic (MRI, DSC-MRI)Experimental Treatment2 Interventions
Participants undergo diagnostic magnetic resonance imaging (MRI) with and without contrast and treatment planning dynamic susceptibility contrast-MRI (DSC-MRI) series before receiving SRS at 4-6 weeks after SRS, and then every 3 months unless clinically indicated sooner.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Dynamic Susceptibility Contrast-MRI (DSC-MRI)
2018
N/A
~10
Magnetic Resonance Imaging (MRI)
2015
Completed Phase 4
~1800

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,658 Previous Clinical Trials
40,924,481 Total Patients Enrolled
Emory UniversityLead Sponsor
1,638 Previous Clinical Trials
2,560,524 Total Patients Enrolled
National Institutes of Health (NIH)NIH
2,696 Previous Clinical Trials
6,952,531 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment in this trial still open to volunteers?

"The clinicaltrials.gov portal states that this trial is no longer actively searching for participants, as the last update to its information was posted on September 30th 2022. Initially published November 28th 2018, it appears 2762 other trials are currently welcoming volunteers."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases
Hui-Kuo Shu 2018. "Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03680144.
~1 spots leftby Apr 2025
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