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Radiation Therapy

SBRT for Liver Metastases

N/A

Waitlist Available

Led By David A Clump, MD

Research Sponsored by Susannah Ellsworth

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 8 years (study population)

Awards & highlights

Study Summary

This trial is testing different doses of radiation to see which is most effective in treating the tumor while minimizing side effects.

Eligible Conditions

Liver Metastases

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 8 years (study population)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 8 years (study population)

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 8 years (study population) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Maximum tolerated dose (MTD)

Secondary outcome measures

Distant failure

Health Related Quality of Life (HRQL)

Local control

+3 more

Side effects data

From 2022 Phase 2 trial • 29 Patients • NCT02045446

79%

Cough

64%

Dyspnea

64%

Nausea

57%

Fatigue

43%

Constipation

36%

Pain

36%

Dizziness

29%

Anemia

29%

Back pain

29%

Vomiting

21%

Chest pain

21%

Lymphocyte count decreased

21%

Death NOS

21%

Anorexia

21%

Anxiety

21%

Fall

14%

Wheezing

14%

Hypotension

14%

Depression

14%

Diarrhea

14%

Dysphagia

14%

Platelet count decreased

14%

Abdominal Pain

14%

Edema

14%

Fever

14%

Headache

14%

Insomnia

14%

Palpitations

Dysuria

Dehydration

Dysgeusia

Hemorrhoids

Amnesia

Hypertension

Confusion

Hypernatremia

Creatinine increased

Dementia

Productive cough

Pneumonitis

White blood cell count decreased

Throat pain

Bone marrow biopsy

Blurred vision

Hearing impaired

Rash

Eye pain

Tachycardia

Lung infection

Neuropathy

Pleuritic pain

Neutropenia

Hypoxia

Aspiration pneumonia

Blood bilirubin increased

Muscle weakness

Tremor

Weight loss

Thrombocytopenia

Floaters

Toothache

Sinusitis

Alopecia

Esophagitis

Otitis externa

Leukocytosis

Edema limbs

Gait disturbance

Parathesia (tingling)

Edema face

COPD

100%

80%

60%

40%

20%

Study treatment Arm

Stereotactic Body Radiation Therapy

Maintenance Chemotherapy

Trial Design

1Treatment groups

Experimental Treatment

Group I: SBRTExperimental Treatment1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Stereotactic Body Radiation Therapy

2012

Completed Phase 2

~780

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Susannah EllsworthLead Sponsor

David A. Clump, MD, PhDLead Sponsor

9 Previous Clinical Trials

347 Total Patients Enrolled

David A Clump, MDPrincipal InvestigatorUPMC Shadyside

6 Previous Clinical Trials

204 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still openings for participation in this clinical experiment?

"Affirmative, clinicaltrials.gov indicates that this research study is actively looking for participants. It was first posted on September 1st 2011 and recently updated on May 17th 2021. 18 candidates are required to join the trial at a single centre."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Stereotactic Body Radiation Therapy (SBRT) for Liver Mets

Susannah Ellsworth 2012. "Stereotactic Body Radiation Therapy (SBRT) for Liver Mets". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01360606.