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Device

Ethos Therapy for Metastasis

N/A
Waitlist Available
Led By Lauren Henke, M.D., M.S.C.I.
Research Sponsored by Washington University School of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through completion of treatment for all enrolled participants (estimated to be 24 months and 2 weeks)
Awards & highlights

Study Summary

This trial is testing a new way to do radiation therapy for brain cancer that may preserve cognitive function better than the standard treatment.

Eligible Conditions
  • Metastasis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through completion of treatment for all enrolled participants (estimated to be 24 months and 2 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and through completion of treatment for all enrolled participants (estimated to be 24 months and 2 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Feasibility of the simulation-free hippocampal-avoidance whole brain radiotherapy (HA-WBRT) as measured by the successful completion of the simulation-free HA-WBRT workflow through treatment delivery

Trial Design

1Treatment groups
Experimental Treatment
Group I: Simulation-Free Hippocampal-Avoidance Whole Brain RadiotherapyExperimental Treatment1 Intervention
A diagnostic MRI-only, simulation-free plan will be generated from diagnostic brain MRI imaging, using a semi-automated, AI-assisted plan template within the Ethos Therapy system. The radiation prescription dose twill be 3.0 Gy daily over approximately 2 weeks for a total of 30.0 Gy (10 fractions).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ethos Therapy
2022
N/A
~10

Find a Location

Who is running the clinical trial?

Washington University School of MedicineLead Sponsor
1,931 Previous Clinical Trials
2,299,699 Total Patients Enrolled
1 Trials studying Metastasis
20 Patients Enrolled for Metastasis
Varian Medical SystemsIndustry Sponsor
58 Previous Clinical Trials
3,729 Total Patients Enrolled
Lauren Henke, M.D., M.S.C.I.Principal InvestigatorWashington University School of Medicine
1 Previous Clinical Trials
10 Total Patients Enrolled

Frequently Asked Questions

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Recent research and studies
clinicaltrials.govStudy
Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device
2022. "Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05096286.
~3 spots leftby Apr 2025
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