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Exercise Therapy for Cancer (EXERT Trial)

N/A
Waitlist Available
Led By Nicholas G Zaorsky, MD
Research Sponsored by Milton S. Hershey Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

EXERT Trial Summary

This trial is testing whether exercise can help ease side effects from radiation therapy for people with metastatic cancer.

Eligible Conditions
  • Metastatic Cancer

EXERT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Acceptability of exercise intervention: (number of patients agreeing to perform RT+ET)/(number approached)
Feasibility of exercise intervention: (number of patients who completed RT+ET)/(number agreeing to perform RT+ET)
Incidence of Treatment- Emergent Adverse Events
Secondary outcome measures
Change in timed up and go
change in grip strength
change in quality of life measured via the Barriers to Exercise RM 5-FM survey
+6 more

EXERT Trial Design

1Treatment groups
Experimental Treatment
Group I: ExerciseExperimental Treatment1 Intervention
The exercise intervention will utilize the "Moving Through Cancer: A Guide to Exercise for Cancer Survivors" framework. A certified cancer exercise physiologist will work through this guide at radiation therapy visits, with at least 1 visit per week, per the study schema. The cancer exercise physiologist will teach participants proper: warm ups, use of equipment, exercise form, modes of activity, intensity of exercise, flexibility exercises, and cool down. The cancer exercise physiologist will tailor the instruction to convey special considerations for exercise based on treatment and cancer type. The patient will perform supervised exercise in the Exercise Medicine Unit under the guidance of the cancer exercise specialist. The exercise done will be educational in nature (i.e. learning about proper walking form, proper intensity for a warmup/cool down, proper techniques for resistance exercises).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exercise Therapy
2013
Completed Phase 3
~750

Find a Location

Who is running the clinical trial?

Milton S. Hershey Medical CenterLead Sponsor
492 Previous Clinical Trials
2,798,806 Total Patients Enrolled
Nicholas G Zaorsky, MDPrincipal InvestigatorPenn State Cancer Institute
Kathryn Schmitz, MDStudy ChairPenn State Cancer Institute

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the main goals of this research project?

"The primary outcome of this study will be the feasibility of the exercise intervention, which will be measured over a one-year period. The secondary outcomes include changes in grip strength and quality of life, as measured by the ECHO EXERT survey and the Work Productivity and Activity Impairment Questionnaire, respectively."

Answered by AI

Are participants still being recruited for this research project?

"Unfortunately, this particular study is no longer looking for patients. The listing was put up on February 12th 2020 but hasn't been updated since October 13th of last year. With that said, there are over 750 other trials actively recruiting right now."

Answered by AI
~3 spots leftby Apr 2025