92 Participants Needed

Nasogastric Tube Decompression for Postoperative Nausea

KA
Overseen ByKatherine A Curry, DDS
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Nova Scotia Health Authority
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study will compare the incidence of postoperative nausea and vomiting during the first 24 hours following corrective jaw surgery (orthognathic surgery) in patients with and without nasogastric tube gastric decompression.

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but if you are taking GLP-1 receptor agonists, you cannot participate.

Is nasogastric tube decompression generally safe for humans?

Nasogastric tube decompression is generally safe, but it can cause side effects like sore throat, nausea, and other discomforts. Studies suggest that routine use may not be necessary and can lead to more complications compared to not using the tube.12345

How does the treatment of no nasogastric tube decompression differ from other treatments for postoperative nausea?

The treatment of no nasogastric tube decompression after surgery is unique because it avoids the routine use of a tube to remove stomach contents, which can lead to fewer complications like sore throat and nausea compared to using the tube. Studies suggest that not using the tube does not significantly affect recovery time or complication rates, making it a viable option for many patients.24678

What data supports the effectiveness of the treatment No NG tube gastric decompression for postoperative nausea?

Research shows that not using a nasogastric tube after surgery does not increase complications like vomiting or delay recovery, and it may reduce sore throat and nausea compared to using the tube.24568

Who Is on the Research Team?

JB

James Brady, DDS/MD

Principal Investigator

NSHA

Are You a Good Fit for This Trial?

This trial is for patients over 16 years old undergoing corrective jaw surgery (orthognathic surgery) at Victoria General Hospital. It includes those having double-jaw or single-jaw surgeries, and those getting a functional genioplasty with another osteotomy.

Inclusion Criteria

I am undergoing surgery on both jaws.
I am over 16 and having surgery to correct a jaw or facial deformity.
I am planning to have jaw surgery.
See 2 more

Exclusion Criteria

I am younger than 16 years old.
I am currently taking GLP-1 receptor agonists.
I am having a surgery to change the shape of my chin.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants undergo orthognathic surgery with or without nasogastric tube gastric decompression

1 day
1 visit (in-person)

Postoperative Monitoring

Participants are monitored for early and delayed postoperative nausea and vomiting (PONV) within the first 24 hours after surgery

24 hours
Continuous monitoring

Follow-up

Participants are monitored for safety and effectiveness after treatment

1-2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • No NG tube gastric decompression
Trial Overview The study compares the occurrence of nausea and vomiting within the first day after orthognathic surgery between patients who have nasogastric tube gastric decompression and those who do not.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: No NG Gastric DecompressionExperimental Treatment1 Intervention
Group II: NG Gastric DecompressionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Nova Scotia Health Authority

Lead Sponsor

Trials
302
Recruited
95,300+

Published Research Related to This Trial

In a randomized trial of 197 patients, postoperative nasogastric tube decompression did not significantly reduce complications or improve recovery compared to no decompression, with only two patients needing decompression in the non-decompression group.
Patients who received nasogastric decompression experienced significantly more sore throat and nausea, suggesting that routine use of this procedure after elective abdominal surgery may not be justified and should be limited to cases with specific complications.
Nasogastric suction after elective abdominal surgery: a randomised study.Nathan, BN., Pain, JA.[2022]
In a study of 174 gastric cancer patients, those with a nasogastric decompression tube experienced significantly lower rates of postoperative symptoms like nausea and sore throat compared to those without the tube.
However, patients without the nasogastric tube had quicker recovery times for ambulation and flatus, suggesting that early removal of the tube is safe and can enhance the quality of life during hospitalization.
[Value of nasogastric decompression tube in patients with gastric cancer].Yu, XF., Wei, YZ., Xue, YW.[2012]
In a study of 535 patients undergoing elective colorectal surgery, routine nasogastric (NG) decompression significantly reduced symptoms like abdominal distention, nausea, and vomiting compared to those who did not receive decompression.
Despite these benefits, there were no significant differences in major complications or length of hospital stay between the two groups, leading to the conclusion that routine NG decompression may not be necessary after such surgeries.
Elective colon and rectal surgery without nasogastric decompression. A prospective, randomized trial.Wolff, BG., Pembeton, JH., van Heerden, JA., et al.[2019]

Citations

Nasogastric suction after elective abdominal surgery: a randomised study. [2022]
[Value of nasogastric decompression tube in patients with gastric cancer]. [2012]
Elective colon and rectal surgery without nasogastric decompression. A prospective, randomized trial. [2019]
Evaluation of the routine use of the nasogastric tube in digestive operation by a prospective controlled study. [2009]
Does the avoidance of nasogastric decompression following elective abdominal colorectal surgery affect the incidence of incisional hernia? Results of a prospective, randomized trial. [2019]
Evidence for early nasogastric tube removal after infrarenal aortic surgery: a randomized trial. [2012]
Systematic nasogastric tube in aortic surgery: is it necessary? [2015]
Randomized Controlled Trial for Evaluation of the Routine Use of Nasogastric Tube Decompression After Elective Liver Surgery. [2018]
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