Genetic Counseling for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This stage I clinical trial compares a genetic counseling patient preference (GCPP) intervention via EHR MyChart patient portal to conventional genetic counseling for women at elevated risk for breast cancer. Women at elevated breast cancer risk may be offered genetic counseling and genetic testing to further define whether they are at high risk (e.g. hereditary risk; BRCA mutation positive); moderate risk (e.g. risk based largely on family history and/or polygenic risk score) or average risk (e.g. general population). Genetic counseling may improve basic genetic knowledge, produce more accurate risk perceptions and tailor recommendations for greater perceived personal control regarding breast cancer risk. A single approach to genetic counseling may not fit the needs for all patients, and genetic counseling models that increase access to genetic testing and are more patient-centered may better serve patients. This trial may help researchers determine if a GCPP intervention can take the place of conventional genetic counseling, while being non-inferior in terms of adherence to screening recommendations, breast cancer genetic knowledge, accurate perception of risk, breast cancer-specific worry, and satisfaction with counseling compared to conventional genetic counseling. Study results will provide the efficacy for using a novel cancer genetic counseling approach via EHR MyChart patient portal that will be readily adaptable to other health care systems in the future, inform best practices, and reduce workforce burden.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is genetic counseling for breast cancer safe for humans?
How does the Genetic Counseling Patient Preference Intervention for breast cancer differ from other treatments?
The Genetic Counseling Patient Preference Intervention, also known as the Know Your Risk (KYR) intervention, is unique because it uses a patient-driven approach to genetic counseling and testing, which can increase accessibility and improve patient experience compared to conventional methods. This intervention leverages technology, such as the EHR MyChart patient portal, to facilitate communication and tailor information to individual patient preferences, making it more efficient and scalable.12467
What data supports the effectiveness of the treatment Genetic Counseling for Breast Cancer?
Research suggests that genetic counseling and testing can play a crucial role in managing breast cancer risk, especially for those at higher risk. The 'Know Your Risk' intervention aims to make genetic counseling more accessible and efficient, potentially improving patient experiences and meeting clinical demands. Additionally, using pre-visit websites and question prompt sheets can enhance communication and patient participation during counseling sessions.12489
Who Is on the Research Team?
Kevin Sweet, MS, LGC
Principal Investigator
Ohio State University Comprehensive Cancer Center
Are You a Good Fit for This Trial?
This trial is for women aged 30-64 who are patients at Ohio State University, use the MyChart portal, and are undergoing routine mammography. They must be at elevated risk for breast cancer as determined by a specific tool but cannot have had previous genetic counseling or testing for cancer risk genes, nor a personal history of certain breast conditions or cancers.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either the GCPP intervention or conventional genetic counseling, including educational videos and genetic test results
Follow-up
Participants are monitored for adherence to NCCN guidelines, breast cancer genetic knowledge, risk perception, and satisfaction with counseling
What Are the Treatments Tested in This Trial?
Interventions
- Conventional Genetic Counseling
- Genetic Counseling Patient Preference Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ohio State University Comprehensive Cancer Center
Lead Sponsor
National Cancer Institute (NCI)
Collaborator