Hydrogen Peroxide for Skin Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing a treatment where a strong hydrogen peroxide solution is applied to skin cancer spots. It targets patients with non-melanoma skin cancers, particularly on the head and neck, to reduce the size of the spots before surgery or other treatments. The hydrogen peroxide works by breaking down cancer cells, potentially leading to smaller treatment areas and better cosmetic outcomes. Hydrogen peroxide has been shown to successfully treat non-melanoma skin cancers by reducing spot size, simplifying removal and healing.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you have used 5-Fluorouracil cream on the lesion in the last 8 weeks, you cannot participate.
Is hydrogen peroxide safe for use on skin?
Hydrogen peroxide is generally safe for skin use in low concentrations (1% to 6%), but higher concentrations (9% to 45%) can cause severe skin damage. It is approved for treating certain skin conditions like seborrheic keratoses and actinic keratosis, with some studies showing it is well tolerated and causes fewer side effects compared to other treatments.12345
How does hydrogen peroxide treatment for skin cancer differ from other treatments?
Hydrogen peroxide treatment for skin cancer is unique because it increases oxygen availability in the skin, which can enhance the effectiveness of photodynamic therapy (a treatment that uses light to activate a drug that kills cancer cells). This approach is different from traditional treatments that may not focus on oxygen levels to improve therapy outcomes.678910
What data supports the effectiveness of the treatment Hydrogen Peroxide 30% Topical Solution for skin cancer?
Who Is on the Research Team?
Jinka Sathya, MD
Principal Investigator
Western University
Are You a Good Fit for This Trial?
Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive topical application of 30% hydrogen peroxide once every week for 4 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
Long-term Follow-up
Participants are monitored for long-term outcomes and adverse events
What Are the Treatments Tested in This Trial?
Interventions
- Hydrogen Peroxide 30 % Topical Solution
Find a Clinic Near You
Who Is Running the Clinical Trial?
London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's
Lead Sponsor
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lead Sponsor
London Health Sciences Centre OR Lawson Research Institute of St. Joseph's
Lead Sponsor
Jinka Sathya
Lead Sponsor
Lawson Health Research Institute
Lead Sponsor