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Aspirin Intolerant Asthma / AERD for Asthma

N/A
Waitlist Available
Led By Spencer C Payne, MD
Research Sponsored by University of Virginia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 hour
Awards & highlights

Study Summary

The purpose of this study is to determine what type of reactions in the body may be responsible for the respiratory symptoms that occur when patients with Aspirin Exacerbated Respiratory Disease (AERD) drink alcoholic beverages. These reactions are most often seen with red wine.

Eligible Conditions
  • Samter's Syndrome
  • Asthma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 hour
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hour for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
24 Hour Urinary Leukotriene-E4 (LTE4)
Secondary outcome measures
24 Hour Urinary Prostaglandin-D2 (PGD2) metabolite
Whole Blood Activated Eosinophil Level
Whole Blood tryptase
+1 more

Trial Design

3Treatment groups
Active Control
Group I: Aspirin Intolerant Asthma / AERDActive Control3 Interventions
Patients with AERD who note sensitivity to alcoholic beverages
Group II: Aspirin Tolerant AsthmaActive Control3 Interventions
Patients with asthma who are tolerant to aspirin and/or other NSAIDs and note sensitivity to alcoholic beverages
Group III: ControlActive Control3 Interventions
Patients without asthma or aspirin intolerance who may or may not react to alcoholic beverages

Find a Location

Who is running the clinical trial?

University of VirginiaLead Sponsor
754 Previous Clinical Trials
1,245,013 Total Patients Enrolled
11 Trials studying Asthma
791 Patients Enrolled for Asthma
Spencer C Payne, MDPrincipal InvestigatorUniversity of Virginia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Mechanisms of Alcohol Sensitivity in AERD
2018. "Mechanisms of Alcohol Sensitivity in AERD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03441438.
~9 spots leftby Apr 2025
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