← Back to Search

Medication Therapy Management (MTM) for Heart Attack (MUMPS Trial)

N/A
Waitlist Available
Led By James AS Muldowney, III, MD
Research Sponsored by Middle Tennessee Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6-9 weeks and 28-32 weeks
Awards & highlights

MUMPS Trial Summary

Existing trials for the patient with coronary heart disease evaluate the interdisciplinary team dynamic where pharmacists (pharmacotherapists) provide therapeutic recommendations in the inpatient environment. To our knowledge, only other trial has evaluated the addition of a pharmacist (or nurse practitioner) in an outpatient collaborative cardiology practice and has found no benefit. However, the investigators believe that since a cardiology based pharmacist (pharmacotherapist) in the Veterans Health Administration has physical assessment skills, a shorter cycle length between appointments, and the ability to provide medication therapy management, the pharmacotherapist should be similarly successful as seen with other pharmacist based medication therapy management practices. The investigators will assess effectiveness by using the combined endpoint of blood pressure and lipid treatment. Additionally the investigators will conduct three substudies to evaluate if the pharmacist can improve all cause mortality and cardiovascular morbidity, adherence to antihypertensives, and patient satisfaction.

Eligible Conditions
  • Heart Attack
  • Coronary Heart Disease

MUMPS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6-9 weeks and 28-32 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6-9 weeks and 28-32 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percentage of patients at guideline goal for both blood pressure and lipids
Secondary outcome measures
Change in Adherence with 8-item Morisky Adherence Tool
Composite cardiovascular morbidity and all-cause mortality
Patient Satisfaction with Clinical Pharmacist Services

MUMPS Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Medication Therapy Management (MTM)Experimental Treatment3 Interventions
Medication Therapy Management visits with a pharmacotherapist will occur at a minimum of 6-9 weeks, 20-24 weeks, and 28-32 weeks. Additional interim face to face and telephonic visits may be scheduled based on patient's progress with meeting treatment goals and need for follow-up physical assessment and laboratory analysis.
Group II: Usual CarePlacebo Group1 Intervention
Visits with a pharmacotherapist to create an accurate list of medications for those patients randomized to placebo (who receive usual care by their cardiologist and primary care provider).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Lifestyle Counseling
2011
Completed Phase 2
~7440

Find a Location

Who is running the clinical trial?

Middle Tennessee Research InstituteLead Sponsor
American Society of Health-System Pharmacists Research and Education FoundationOTHER
3 Previous Clinical Trials
167 Total Patients Enrolled
James AS Muldowney, III, MDPrincipal InvestigatorVA Tennessee Valley Healthcare System

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~12 spots leftby Apr 2025