Music vs Mindfulness for Cardiovascular Health

(CMM Trial)

Overseen By Sara de la Salle, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Sir Mortimer B. Davis - Jewish General Hospital

Must not be taking: Blood pressure medications

Disqualifiers: Hearing impairments, Hypertension, Cardiovascular disease, Substance use disorder, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to examine how listening to music compares to guided mindfulness in affecting blood pressure, heart rate, and feelings of anxiety in healthy adults. The investigators aim to determine whether one of these approaches is more effective in reducing these variables. Additionally, the study will explore whether personal traits or preferences, measured using questionnaires, influence how participants respond to music or mindfulness. Based on previous clinical findings, the researchers hypothesize that listening to music will lead to greater reductions in blood pressure and heart rate compared to guided mindfulness.

Who Is on the Research Team?

Kyle Greenway, MD

Principal Investigator

Sir Mortimer B. Davis - Jewish General Hospital, McGill University

Are You a Good Fit for This Trial?

This trial is for healthy adults interested in seeing how music or guided mindfulness can affect their heart rate, blood pressure, and anxiety levels. Participants should be willing to answer questionnaires about personal traits and preferences.

Inclusion Criteria

Normal baseline blood pressure (systolic BP < 120 mmHg and diastolic BP < 80mmHg)

I can avoid nicotine or tobacco for 1 hour before and during the study session.

Abstention from caffeine intake for at least 12 hours before the study session and throughout the session, as caffeine may influence cardiovascular measurements

Exclusion Criteria

I have a history of high blood pressure or heart disease.

I have a substance use disorder that could affect my heart.

Significant hearing impairments that cannot be improved with hearing aids or sound amplification

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Study Visit

Participants attend a single 3-hour study visit involving two sessions: music listening and guided mindfulness, with a 20-minute washout period in between.

1 day

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the intervention sessions

1-2 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Mindfulness
• Music

Trial Overview

The study is testing the effects of listening to music versus practicing guided mindfulness on cardiovascular health and anxiety. It aims to find out which method is more effective at reducing blood pressure, heart rate, and feelings of stress.

How Is the Trial Designed?

Group I: Music Intervention First Experimental Treatment 2 Interventions

Participants randomized to this arm will receive a 40-minute Music Listening intervention in the first period, followed by a 20-minute washout period, and then receive a 40-minute Guided Mindfulness intervention in the second period.

Group II: Mindfulness Intervention First Experimental Treatment 2 Interventions

Participants randomized to this arm will receive a 40-minute Guided Mindfulness intervention in the first period, followed by a 20-minute washout period, and then receive a 40-minute Music Listening intervention in the second period.

Who Is Running the Clinical Trial?

Sir Mortimer B. Davis - Jewish General Hospital

Lead Sponsor

Trials

61

Recruited

25,800+