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Exercise Testing and Training for Chronic Musculoskeletal Pain (EXCPPTSD Trial)

N/A
Waitlist Available
Led By Erica R. Scioli, PhD
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, midpoint (at 6 weeks) and endpoint (at 13 weeks)
Awards & highlights

EXCPPTSD Trial Summary

This trial will study whether a chronic progressive exercise program will reduce chronic pain in patients with PTSD, and modify any potential PTSD-related deficiencies in neurobiological and psychological responses to exercise.

Eligible Conditions
  • Chronic Musculoskeletal Pain
  • Post-Traumatic Stress Disorder
  • Traumatic Brain Injury

EXCPPTSD Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, midpoint (at 6 weeks) and endpoint (at 13 weeks)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, midpoint (at 6 weeks) and endpoint (at 13 weeks) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from Baseline: Clinician Administered PTSD Scale -5
Change from Baseline: West Haven=Yale Multidimensional Pain Inventory- Interference Subscale (WHY-MPI)

EXCPPTSD Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Chronic Pain//PTSD groupExperimental Treatment1 Intervention
This group will receive baseline and endpoint maximum load exercise testing which will inform their individualized exercise prescription (based on a progressive methodology) of aerobic exercise training aimed at meeting specific heart rate ranges over time (increasing up to 80% of maximum HRR between the midpoint and endpoint (6-12 weeks).
Group II: Trauma-exposed healthy control groupActive Control1 Intervention
This group will receive baseline and endpoint maximum load exercise testing which will inform their individualized exercise prescription (based on a progressive methodology) of aerobic exercise training aimed at meeting specific heart rate ranges over time (increasing up to 80% of maximum HRR between the midpoint and endpoint (6-12 weeks).

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,609 Previous Clinical Trials
3,306,579 Total Patients Enrolled
6 Trials studying Chronic Musculoskeletal Pain
6,834 Patients Enrolled for Chronic Musculoskeletal Pain
Erica R. Scioli, PhDPrincipal InvestigatorVA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
1 Previous Clinical Trials
17 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD
2013. "Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03283163.
All > American Chronic Pain > Psychological
~2 spots leftby Apr 2025
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