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Cool Room Treadmill Training for Multiple Sclerosis

N/A

Waitlist Available

Led By Michelle Ploughman, PhD

Research Sponsored by Memorial University of Newfoundland

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged older than 18 and less than 70 years

People with a confirmed diagnosis of relapsing-remitting or progressive MS

Timeline

Screening 3 weeks

Treatment Varies

Follow Up following completion of the 12-week exercise intervention and 3-months post-exercise intervention

Awards & highlights

Study Summary

This trial will test how effective a more intense form of exercise is in people with MS who have fatigue and heat-sensitivity.

Who is the study for?

This trial is for people aged 18-70 with a confirmed diagnosis of relapsing-remitting or progressive Multiple Sclerosis. Participants should be stable without MS relapse for at least 90 days and able to walk at least 10 meters, even if they need walking aids.Check my eligibility

What is being tested?

The study tests vigorous intensity treadmill training in a cool room (16°C) against low-intensity training to see which is better for restoring functions lost due to MS. The focus is on finding the right amount of exercise that can be tolerated by those who experience fatigue and heat sensitivity from MS.See study design

What are the potential side effects?

Potential side effects may include muscle soreness, fatigue, and temporary worsening of MS symptoms due to physical exertion or reactions to cooler temperatures during the exercise.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am between 19 and 69 years old.

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I have been diagnosed with relapsing-remitting or progressive MS.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ following completion of the 12-week exercise intervention and 3-months post-exercise intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~following completion of the 12-week exercise intervention and 3-months post-exercise intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and following completion of the 12-week exercise intervention and 3-months post-exercise intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Fast walking speed

Secondary outcome measures

Fatigue Severity Scale

Hospital Anxiety and Depression Scale

Maximal oxygen consumption during graded exercise test

+7 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Vigorous Intensity GroupExperimental Treatment1 Intervention

More than 60% Heart Rate Reserve

Group II: Low Intensity GroupActive Control1 Intervention

Less than 40% Heart Rate Reserve

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Memorial University of NewfoundlandLead Sponsor

68 Previous Clinical Trials

1,831,952 Total Patients Enrolled

2 Trials studying Multiple Sclerosis

62 Patients Enrolled for Multiple Sclerosis

Multiple Sclerosis Society of CanadaOTHER

14 Previous Clinical Trials

931 Total Patients Enrolled

14 Trials studying Multiple Sclerosis

931 Patients Enrolled for Multiple Sclerosis

Michelle Ploughman, PhDPrincipal InvestigatorMemorial University of Newfoundland

1 Previous Clinical Trials

52 Total Patients Enrolled

Media Library

Body-weight supported treadmill training in a room cooled to 16°C Clinical Trial Eligibility Overview. Trial Name: NCT04175054 — N/A

Multiple Sclerosis Research Study Groups: Vigorous Intensity Group, Low Intensity Group

Multiple Sclerosis Clinical Trial 2023: Body-weight supported treadmill training in a room cooled to 16°C Highlights & Side Effects. Trial Name: NCT04175054 — N/A

Body-weight supported treadmill training in a room cooled to 16°C 2023 Treatment Timeline for Medical Study. Trial Name: NCT04175054 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are adolescents eligible for this clinical trial?

"The study's eligibility requirements state that patients must be between 18-70 years old to participate."

Answered by AI

Are new patients currently being enrolled in this research?

"No, this research is not looking for new volunteers. Although the trial originally posted on January 1st, 2022, the most recent update was on August 31st, 2021. Even though this specific study is not looking for new additions, there are 661 other clinical trials that are."

Answered by AI

Do I fit the eligibility criteria to join this clinical trial?

"The ideal candidate for this medical trial should be between 18 and 70 years of age and have some degree of neuronal plasticity. So far, 70 people have been recruited."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Comparison of Vigorous Versus Low Intensity Cool Room Treadmill Training in People With Multiple Sclerosis

Michelle Ploughman 2023. "Comparison of Vigorous Versus Low Intensity Cool Room Treadmill Training in People With Multiple Sclerosis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04175054.

All > Multiple Sclerosis