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Hyperbaric Oxygen Treatment for Hodgkin's Lymphoma (Auto-HBO Trial)

N/A
Waitlist Available
Led By Omar Aljitawi, MD
Research Sponsored by University of Kansas Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up assessment at: day -7 (lymphoma) or day -3 (myeloma), pre-hbo (day 0), pre-transplant (6-10hrs post-hbo), 24 and 48 hrs after starting hyperbaric oxygen treatment as well as 3 days post-neutrophil engraftment
Awards & highlights

Auto-HBO Trial Summary

By doing this study, researchers hope to learn the following: The safety of hyperbaric oxygen administration in the setting of the autologous transplant The effects of hyperbaric oxygen administration on neutrophil count recovery and engraftment

Eligible Conditions
  • Hodgkin's Lymphoma
  • Multiple Myeloma
  • Non-Hodgkin's Lymphoma

Auto-HBO Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~assessment at: day -7 (lymphoma) or day -3 (myeloma), pre-hbo (day 0), pre-transplant (6-10hrs post-hbo), 24 and 48 hrs after starting hyperbaric oxygen treatment as well as 3 days post-neutrophil engraftment
This trial's timeline: 3 weeks for screening, Varies for treatment, and assessment at: day -7 (lymphoma) or day -3 (myeloma), pre-hbo (day 0), pre-transplant (6-10hrs post-hbo), 24 and 48 hrs after starting hyperbaric oxygen treatment as well as 3 days post-neutrophil engraftment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Presence or absence of a treatment limiting toxicity
Secondary outcome measures
Reduction in time to neutrophil recovery and engraftment post-cord blood transplant.
Other outcome measures
Examine correlation between change to erythropoietin (EPO) levels and time to neutrophil recovery and engraftment.
Explore the effects of hyperbaric oxygen (HBO) therapy on erythropoietin (EPO) levels.

Auto-HBO Trial Design

1Treatment groups
Experimental Treatment
Group I: Hyperbaric Oxygen TreatmentExperimental Treatment1 Intervention
Administration of hyperbaric oxygen on the morning of stem cell transplant (Day 0).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Administration of hyperbaric oxygen
2013
N/A
~20

Find a Location

Who is running the clinical trial?

Southwest Oncology GroupNETWORK
388 Previous Clinical Trials
261,791 Total Patients Enrolled
University of Kansas Medical CenterLead Sponsor
464 Previous Clinical Trials
169,255 Total Patients Enrolled
SWOG Cancer Research NetworkNETWORK
394 Previous Clinical Trials
265,150 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Pilot Study Exploring the Use of Hyperbaric Oxygen in Autologous Peripheral Blood Stem Cell Transplantation
2014. "Pilot Study Exploring the Use of Hyperbaric Oxygen in Autologous Peripheral Blood Stem Cell Transplantation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02087657.
All > Stem Cell Transplant
~2 spots leftby May 2025
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