This trial is evaluating whether Education will improve 2 primary outcomes and 2 secondary outcomes in patients with Multiple Myeloma. Measurement will happen over the course of Day 0 (date cells are infused) to 12-months post-transplant.
This trial requires 30 total participants across 1 different treatment group
This trial involves a single treatment. Education is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"The most common treatments for primary multiple myeloma include supportive care and drug regimens; they are usually based on the age of the patient. Treatment regimens including corticosteroids, bortezomib, or autophagy inhibitors are not available in most jurisdictions and may only benefit a small fraction of cases. Although multiple myeloma can often be treated over one to two years in first disease, most patients will have a relapse in the subsequent years." - Anonymous Online Contributor
"The signs of [multiple myeloma](https://www.withpower.com/clinical-trials/multiple-myeloma) include bone pain and an unfavourable attitude, but the most specific sign of multiple myeloma is plasma cell dyscrasia. It may therefore be necessary to investigate for multiple myeloma whenever an unresponsive myeloma patient has a plasma cell phenotype. Multiple myeloma patients may be misdiagnosed as a case of autoimmune diabetes in the elderly or another autoimmune disease if signs are restricted to high-dose glucocorticoid treatment." - Anonymous Online Contributor
"Approximately 20,000 new cases of MM are diagnosed a year in the United States. question: Does low vitamin D status predict the progression from IgA1 nephropathy to proliferative lupus nephritis? answer: Data from a recent study reveals that vitamin D is associated with the progression from IgA1N to PMLN. Vitamin D levels are not associated with the development of IgA1N to IgAN. Further studies are needed to investigate the usefulness of vitamin D supplements for the prevention of PMLN." - Anonymous Online Contributor
"Although the incidence of MM in the United States has increased 10-fold over the last 45 years, survival has maintained a trend toward improvement, likely because of the development of more effective and more frequent treatment options and improved control of MM-related hematologic manifestations." - Anonymous Online Contributor
"While some of our patients had very minimal and mild, yet still present, clinical response to bortezomib treatment, no patients ever had a complete remission or complete responses. Some patients had progressive disease with a response to bortezomib and then subsequent rapid progression of disease thereafter. As with all antitumor agents, careful patient selection before beginning treatment as well as follow up during treatment are important to minimize any effects of therapy on disease progression. We also noted in some patients a very short follow-up interval and thus limited insight regarding prolonged responses to bortezomib. Long-term studies are necessary to clarify its role in treating multiple myeloma." - Anonymous Online Contributor
"The exact causes are unknown, but it is known to be related to genetic factors and cancer. As more people with myeloma survive a diagnosis of multiple myeloma is often the result." - Anonymous Online Contributor
"[Education is a highly successful intervention for a variety of health conditions such as coronary heart disease, stroke, cancer, diabetes and osteoarthritis, because it improves knowledge and attitudes, improves self-care, improves adherence with treatment, and leads to behavioral improvements (http://www.ncommsnet.org/content/article/1/4_cite." - Anonymous Online Contributor
"Patients with [multiple myeloma](https://www.withpower.com/clinical-trials/multiple-myeloma) have a better quality of life following treatment. There is evidence that exercise in multiple myeloma patients can provide benefit for quality of life and that this might have clinical implications. There is still little research available on the effect of exercise on survival in this disease. There is however a clear need for research, particularly for exercise training interventions with myeloma patients." - Anonymous Online Contributor
"In the US, multiple myeloma occurs mainly in the aged; only around 0.5 to 1.0% of all people are under age 60. In Europe, the age at diagnosis of multiple myeloma has shifted since 1990 to earlier ages (56-60 years, as of 2009 at the age of diagnosis, up from 35 years during the 1970s-1980s), and is now similar to the incidence reported in Canada (2009)." - Anonymous Online Contributor
"Improving quality of life in patients with MM requires an effective plan tailored to each individual patient. The addition of education to standard palliative care interventions in this setting does not improve quality of life. Given that health beliefs can affect patients' quality of life, interventions that address patients' beliefs and attitudes to care may be more effective in improving the quality of life of individuals with MM." - Anonymous Online Contributor
"Patients diagnosed with MM have been consistently associated with earlier ages of presentation and more aggressive disease at diagnosis, and also shorter overall survival. MM tends to occur more frequently in older males, thus male and female MM incidence rates are relatively equal. MM is also less often diagnosed among African Americans compared with other ethnicities." - Anonymous Online Contributor
"In a large group of people undergoing an elective elective surgical procedure, education alone did not reduce morbidity or complications. However, this study cannot refute the important benefits education may have on patient's comprehension, adherence and satisfaction at the time of any procedure. Further evaluations are now required to establish the full implications of education for the health of patients." - Anonymous Online Contributor