ProDentis Lozenge for Oral Cancers

Phase-Based Progress Estimates
University of Iowa College of Dentistry and Dental Clinics, Iowa City, IAOral CancersProDentis Lozenge - DietarySupplement
21 - 89
All Sexes
What conditions do you have?

Study Summary

This trial is investigating how changes in the types of bacteria in the mouth may be related to the most common type of oral cancer, and whether a probiotic regimen may help prevent or rectify these changes.

Eligible Conditions
  • Oral Cancers

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: Up to 3 months

Up to 3 months
Assessment of changes in the oral microbiome composition over time
Determine the Effect of ProDentis on the Oral Microbiome

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Probiotic Lozenge
1 of 2
Placebo Lozenge
1 of 2

Experimental Treatment

Non-Treatment Group

24 Total Participants · 2 Treatment Groups

Primary Treatment: ProDentis Lozenge · Has Placebo Group · N/A

Probiotic Lozenge
Experimental Group · 1 Intervention: ProDentis Lozenge · Intervention Types: DietarySupplement
Placebo Lozenge
PlaceboComparator Group · 1 Intervention: Placebo Lozenge · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to 3 months

Who is running the clinical trial?

University of IowaLead Sponsor
420 Previous Clinical Trials
878,899 Total Patients Enrolled
David Drake, MS, PhDPrincipal InvestigatorUniversity of Iowa College of Dentistry

Eligibility Criteria

Age 21 - 89 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are an adult between the ages of 21 and 70 and have been diagnosed with oral squamous cell carcinoma, or you are a healthy person without any oral lesions who matches the criteria.

Frequently Asked Questions

Are there still opportunities available for participants in this experiment?

"According to the website, this research initiative is currently recruiting participants. It was posted on April 20th 2022 and its most recent update took place in August 4th of the same year." - Anonymous Online Contributor

Unverified Answer

Does the study accept participants who have surpassed 35 years of age?

"According to the criteria for enrolment, this medical trial requires participants of legal age or older and no more than 89 years old." - Anonymous Online Contributor

Unverified Answer

How many individuals are currently engaged in this experiment?

"Affirmative. According to the website, recruitment for this trial began on April 20th 2022 and was last updated on August 4th 2022. This study is looking for 24 individuals from a single site." - Anonymous Online Contributor

Unverified Answer

What are the eligibility requirements for participation in this trial?

"This clinical trial has a participant cap of 24 individuals, all of whom must possess oral neoplasms and be between the ages 21 and 89." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.