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LED Light Therapy for Seasonal Affective Disorder

N/A

Waitlist Available

Led By Janis L Anderson, Ph.D

Research Sponsored by Brigham and Women's Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

History of recurrent major depressive episodes with winter-type seasonal pattern by DSM-IV criteria

Free of medical illness, not pregnant, as determined by detailed history and physical examination including blood and urine chemistries and thyroid function tests

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial will compare the efficacy and tolerability of two light sources for the treatment of seasonal affective disorder.

Who is the study for?

This trial is for adults with Seasonal Affective Disorder (SAD), who experience recurrent major depressive episodes in fall/winter. Participants must be medically healthy, not pregnant, and free from certain medications or conditions that could affect mood or interfere with the study.Check my eligibility

What is being tested?

The trial tests two types of LED light therapy: one using narrow-wavelength blue light and another using broad-wavelength white light to treat SAD symptoms. Patients will use a portable device at home for three weeks and have their depression levels monitored weekly.See study design

What are the potential side effects?

Potential side effects are not specified but will be monitored during the trial. The study aims to compare adverse effects between narrow-wavelength (blue) and broad-wavelength (white) LED light sources.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had repeated major depression episodes during winter.

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I am not pregnant and have no major illnesses, as confirmed by tests.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

score on depression rating scale at weeks 1, 2, and 3 by rater blind to treatment condition

Secondary outcome measures

adverse effects reported to rater blind to treatment condition

score on hypomania/mania rating scale at weeks 1, 2, and 3

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Brigham and Women's HospitalLead Sponsor

1,618 Previous Clinical Trials

11,471,686 Total Patients Enrolled

Janis L Anderson, Ph.DPrincipal InvestigatorBrigham and Women's Hospital

Media Library

LED Light Clinical Trial Eligibility Overview. Trial Name: NCT00114322 — N/A

Seasonal Affective Disorder Research Study Groups:

Seasonal Affective Disorder Clinical Trial 2023: LED Light Highlights & Side Effects. Trial Name: NCT00114322 — N/A

LED Light 2023 Treatment Timeline for Medical Study. Trial Name: NCT00114322 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age limitation for enrollment to this trial beyond seventy-five years of age?

"This trial is taking applicants who are of legal age and under 64 years old."

Answered by AI

Are there any vacancies open to participants in this trial?

"As per the clinicaltrials.gov page, this trial is not currently seeking patients as it has been inactive since 1/12/2007--the date of its last edit. Nonetheless, there are 81 other trials in progress with open recruitment slots at present."

Answered by AI

Who is eligible to take part in this research trial?

"This medical trial seeks 24 volunteers suffering from winter depression, who have not reached 65 years old yet. Additionally, it is essential that participants are without any other illnesses, and prove their non-pregnancy through a set of biochemical tests as well as thyroid function evaluations."

Answered by AI

Recent research and studies

Acta Psychiatrica ScandinavicaJournal

Lux Vs. Wavelength in Light Treatment of Seasonal Affective Disorder

Anderson, J. L., C. A. Glod, J. Dai, Y. Cao, and S. W. Lockley. 2009. “Lux Vs. Wavelength in Light Treatment of Seasonal Affective Disorder”. Acta Psychiatrica Scandinavica. Wiley. doi:10.1111/j.1600-0447.2009.01345.x.

clinicaltrials.govStudy

Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment

2005. "Light-Emitting Diode (LED) Light for Seasonal Affective Disorder (SAD) Treatment". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00114322.

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