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High-Intensity Exercise for Older Adults with HIV (HEALTH Trial)

N/A

Recruiting

Led By Kristine Erlandson, MD

Research Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Fatigued (≥2.0 on either of the first two screening items on the HIV-Related Fatigue Scale)

Aged ≥ 50 years

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 0-16 weeks

Awards & highlights

HEALTH Trial Summary

This trial will test whether high-intensity interval training or continuous moderate-intensity exercise, with or without biobehavioral coaching, can help people with HIV aged 50-80 who experience fatigue and live a sedentary lifestyle.

Who is the study for?

This trial is for adults aged 50-80 with HIV who are sedentary, experience fatigue, and have been on stable antiretroviral therapy with a controlled viral load. They must be willing to commit to a 16-week exercise program and have no major health issues like severe heart disease or uncontrolled diabetes that could interfere with safe participation.Check my eligibility

What is being tested?

The study compares high-intensity interval training (HIIT) against continuous moderate-intensity exercise (CME) in improving physical function, reducing fatigue, and enhancing mitochondrial bioenergetics in older adults living with HIV. It also tests if biobehavioral coaching can help maintain long-term physical activity habits after the intervention.See study design

What are the potential side effects?

Potential side effects from participating in this exercise trial may include muscle soreness, joint pain, or injury due to increased physical activity. Participants will be monitored for any adverse reactions related to the intensity of the exercises.

HEALTH Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I often feel very tired.

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I am 50 years old or older.

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I am 50 years old or older.

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I have received all recommended COVID-19 vaccinations and boosters.

HEALTH Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0-16 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0-16 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0-16 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in physical function

Secondary outcome measures

Change in fatigue

HEALTH Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: High intensity interval trainingExperimental Treatment1 Intervention

Group II: Continuous moderate intensity exerciseActive Control1 Intervention

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of WashingtonOTHER

1,741 Previous Clinical Trials

1,847,646 Total Patients Enrolled

University of Colorado, DenverLead Sponsor

1,738 Previous Clinical Trials

2,149,406 Total Patients Enrolled

Case Western Reserve UniversityOTHER

299 Previous Clinical Trials

246,462 Total Patients Enrolled

Media Library

HIIT (intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04550676 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research endeavor presently accepting participants?

"Affirmative. The clinicaltrials.gov website has the most up-to-date information, which confirms that current recruitment is still underway for this trial posted on April 2nd 2021 and edited February 1st 2022. Two medical centres are looking to enrol 100 subjects in total."

Answered by AI

To what capacity is the clinical trial recruiting participants?

"Affirmative. According to the clinicaltrials.gov records, this experiment is recruiting participants at present. It was initially advertised on April 2nd 2021 and its details were last modified on February 1st 2022; it requires a total of 100 volunteers between two sites."

Answered by AI