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Behavioural Intervention

AI-Powered Remote Dental Monitoring for Misaligned Teeth

N/A
Recruiting
Research Sponsored by Mohammed H Elnagar
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients who request clear aligner treatment with the sole aim of correcting dental alignment
Upper or lower labial segment crowding, malocclusion to be treated with more than 20 Clear Aligners
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 to 30 months
Awards & highlights

Study Summary

This trial aims to use a new AI-powered 3D tooth monitoring technology to customize aligner changing intervals and reduce in-office visits while maintaining treatment results.

Who is the study for?
This trial is for people with misaligned teeth or malocclusion who need more than 20 clear aligners and are at least 12 years old with all permanent teeth (except wisdom teeth). They should want to correct dental alignment without extractions. It's not for those with gum disease, a history of certain bone treatments, dental prostheses, tooth anomalies, other appliance use, systemic diseases or syndromes, or current NSAID users.Check my eligibility
What is being tested?
The study tests if using Dental MonitoringTM technology along with AI algorithms can better customize the timing of changing clear aligners compared to standard practices. The goal is to potentially reduce office visits and overall treatment time while still closely monitoring progress remotely during orthodontic treatment.See study design
What are the potential side effects?
Since this trial involves non-invasive technology rather than medication, traditional side effects aren't expected. However, there may be issues related to comfort and convenience when adapting to remote monitoring tools.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I want clear aligners just to straighten my teeth.
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I need treatment for crowded teeth requiring over 20 clear aligners.
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I have all my adult teeth, except for wisdom teeth.
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I am 12 years old or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 to 30 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 to 30 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of refinement aligners
Number of refinements plans
The number of aligners trays completed with an adequate fit
+1 more
Secondary outcome measures
ABO Discrepancy Index
Tooth structure
The American Board of Orthodontics (ABO) Objective grading system (OGS)
Other outcome measures
Number of office visits
Patient compliance

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Clear Aligners with Dental MonitoringExperimental Treatment1 Intervention
Experiment group: DM (Remote Dental Monitoring approach). Remote Dental Monitoring by DMTM will be implemented in the patient's orthodontic treatment. Pretreatment, 3D digital intra-oral scans will be uploaded to the DMTM dashboard, so they serve as the baseline for 3D tracking of tooth movement. Patients will be trained on how to use the DMTM application and do DM remote scans using their smartphones DM scan box and rector. They will be instructed to do the DM scan after the initial tray insertion. Replacement of the aligners trays will be based on DM GO tracking function, which is specifically targeted at clear aligner treatment.
Group II: Clear Aligners replaced every 7 daysActive Control1 Intervention
Group 2:Control group. All subjects will have conventional aligner treatment with aligners replaced every 7 days, and standard in-office visits every 8 weeks.
Group III: Clear Aligners replaced every 14 daysActive Control1 Intervention
Group 3: (n=40) Control group. All subjects will have conventional aligner treatment with aligners replaced every 14 days, and standard in-office visits every 8 weeks.

Find a Location

Who is running the clinical trial?

Mohammed H ElnagarLead Sponsor

Media Library

Optimizing Orthodontic Appliances Efficiency (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05573308 — N/A
Optimizing Orthodontic Appliances Efficiency (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05573308 — N/A
Misaligned Teeth Research Study Groups: Clear Aligners with Dental Monitoring, Clear Aligners replaced every 7 days, Clear Aligners replaced every 14 days
Misaligned Teeth Clinical Trial 2023: Optimizing Orthodontic Appliances Efficiency Highlights & Side Effects. Trial Name: NCT05573308 — N/A
Misaligned Teeth Patient Testimony for trial: Trial Name: NCT05573308 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are medical professionals continuing to enroll participants into this research study?

"According to clinicaltrials.gov, this research initiative is still open and recruiting participants. It was first listed on the 1st of October 2022 with the most recent update occurring on 6th of October that same year."

Answered by AI

Are there multiple sites across the United States where this experiment is taking place?

"The Department of Orthodontics, College of Dentistry University of Illinois Chicago (Chicago), Orthodontic Specialists of Lake County (Grayslake) and Orthodontic Specialists of Lake County (Gurnee), as well as four additional sites are participating in this research trial."

Answered by AI

How many individuals have signed up for this clinical trial so far?

"That is correct. Clinicaltrials.gov illustrates that this experiment, which was initially listed on October 1st 2022, is actively recruiting participants. 12 individuals need to be recruited from 4 different medical sites around the country."

Answered by AI

Who meets the requirements to take part in this medical experiment?

"This study is searching for 12 individuals with a crossbite, ranging from the age of 12 to 70. Notably, they must meet these additional conditions: desire Clear Aligner treatment to correct dental alignment only; have full permanent teeth (except third molars); no extractions involved in the procedure; upper or lower labial segment overcrowding as well as misalignment needing more than 20 aligners."

Answered by AI

Is the eligibility criteria for this clinical trial limited to those over 18 years of age?

"To partake in this trial, applicants must be aged between 12 and 70. In addition to this main trial, there are 38 sub-trials for minors and 11 studies catered towards elderly patients over the age of 65."

Answered by AI

Who else is applying?

What state do they live in?
New York
West Virginia
California
What site did they apply to?
Orthodontic Specialists of Lake County (Gurnee)
Orthodontic Specialists of Lake County (Grayslake)
Department of Orthodontics, College of Dentistry University of Illinois Chicago
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

My mom cant afford to fix my teeth. Kids pick on me. I can’t afford orthodontist treatment because I am not covered and over the age.
PatientReceived no prior treatments
I had braces as a kid and my teeth have gotten significantly more crowded and out of alignment and my bite has greatly worsened. I’ve always thought about fixing it, but it was never the right time. It would be fascinating to be a part of AI trials to further improve people’s experience of oral care.
PatientReceived 2+ prior treatments
~7 spots leftby Dec 2025