Neuroimaging for Migraine
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to understand changes in the brain's white matter (a type of brain tissue) in women who experience migraines. Participants will undergo brain neuroimaging (brain scans) to determine if these changes relate to migraines, small vessel ischemic (SVI) disease, or multiple sclerosis (MS). Women with migraines, SVI disease, or MS who have specific brain changes seen on an MRI are a good fit for this study. As an unphased trial, this study offers participants a unique opportunity to contribute to groundbreaking research that could enhance understanding of brain changes associated with these conditions.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team for clarification.
What prior data suggests that brain neuroimaging is safe for women with migraines?
Research has shown that brain scans are safe tools for studying the brain. They do not involve taking medicine or any invasive procedures. Instead, they use MRI (magnetic resonance imaging), a common and non-invasive method for capturing brain images.
People often undergo MRIs for health checks and generally tolerate them well. The MRI process itself has no known major side effects. Participants might experience temporary discomfort from lying still during the scan or hearing loud noises.
In studies examining brain scans in people with migraines, researchers have observed changes in certain brain areas. However, these studies aim to enhance understanding of the brain and do not suggest any safety risks from the imaging process. Thus, the brain scanning part of this study is considered safe for participants.12345Why are researchers excited about this trial?
Researchers are excited about the use of brain neuroimaging for migraines because it offers a new way to understand and potentially manage the condition. Unlike standard migraine treatments, which typically focus on relieving symptoms or preventing attacks with medications, this approach uses advanced imaging techniques to visualize the brain's structure and activity. By identifying white matter hyperintensities (WMHs) in the brain, neuroimaging might reveal underlying patterns or triggers associated with migraines. This could lead to more personalized treatment plans and a deeper understanding of migraines, ultimately improving patient outcomes.
What evidence suggests that brain neuroimaging is effective for understanding white matter hyperintensities in women with migraines?
Research shows that people with migraines are more likely to have certain brain changes, called white matter hyperintensities (WMH), than those without migraines. MRI scans reveal that these changes are linked to longer durations of migraines. Studies indicate that WMHs can increase the risk of other health issues like stroke and dementia. This trial will include a migraine cohort, where women with migraines and WMH will undergo brain neuroimaging. Understanding these brain changes in migraine patients could help predict and manage these risks. Therefore, brain imaging for migraines aims to provide insights into these patterns and their potential impact on health.678910
Who Is on the Research Team?
Catherine Chong, PhD
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
This study is specifically for women aged 20-45 who have white matter hyperintensities (WMH) on their brain MRI, which can be related to conditions like migraines or small vessel disease.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging Assessment
Participants undergo brain neuroimaging to assess white matter hyperintensities
Follow-up
Participants are monitored for safety and effectiveness after imaging assessment
What Are the Treatments Tested in This Trial?
Interventions
- Brain Neuroimaging
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor