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Physical Inactivity Duration for Metabolism

N/A

Recruiting

Led By Jieting Wang, M.S.

Research Sponsored by University of Texas at Austin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

No injury or disease affecting the cycling ability

Healthy male or female between the age of 18-65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up a total of 5 measurements will be done, specifically are before the high fat meal (baseline) and each hour after the high fat meal for 4 hours. the whole test takes about 5 hours from 9 am to 2 pm on the last day of each trial.

Awards & highlights

Study Summary

This trial looks into how long periods of inactivity affect fat burning after exercise. Healthy people will do 3 trials varying in inactivity length and exercise intensity.

Who is the study for?

This trial is for healthy men and women aged 18-65 who are untrained or recreationally active, without any injuries affecting cycling, metabolic diseases, lactose intolerance, or on medication that changes lipid/carb metabolism. Those with heart issues, hypertension, respiratory problems, exercise-induced chest pain or fainting can't join.Check my eligibility

What is being tested?

The study examines how different lengths of physical inactivity (12h, 24h, 36h) affect fat levels in the blood and fat burning after morning exercise. It's a crossover study where each participant goes through all three inactive periods plus a control phase with regular activity and tests involving cycling and high-fat meals.See study design

What are the potential side effects?

Since this trial involves periods of inactivity rather than medication intake there may not be direct side effects like those from drugs; however prolonged physical inactivity could potentially lead to muscle stiffness or temporary decreases in metabolic rate.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I can cycle without any issues caused by injury or disease.

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I am between 18 and 65 years old and healthy.

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I don't have metabolic diseases, lactose intolerance, or take meds affecting my lipid or carb metabolism.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ a total of 5 measurements will be done, specifically are before the high fat meal (baseline) and each hour after the high fat meal for 4 hours. the whole test takes about 5 hours from 9 am to 2 pm on the last day of each trial.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~a total of 5 measurements will be done, specifically are before the high fat meal (baseline) and each hour after the high fat meal for 4 hours. the whole test takes about 5 hours from 9 am to 2 pm on the last day of each trial.

This trial's timeline: 3 weeks for screening, Varies for treatment, and a total of 5 measurements will be done, specifically are before the high fat meal (baseline) and each hour after the high fat meal for 4 hours. the whole test takes about 5 hours from 9 am to 2 pm on the last day of each trial. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Fat oxidation (fat burning)

Plasma triglyceride

Trial Design

3Treatment groups

Experimental Treatment

Group I: 36-hr trialExperimental Treatment1 Intervention

Participants will go through a 48-hr physical activity control phase with 10,000 steps taken every 24 hours (9 pm to 9 pm the next day). This phase will be followed with a 36-hour physical inactive phase (9 pm - 9 am on the high fat tolerance day). During the inactive phase, it includes two 12 hours that mostly at night (9 pm - 9 am the next day) and one 12 hours (9 am to 9 pm the same day) that mostly in the day. Less than 1,500 steps is required for 9 pm - 9 am periods, and less than 1,000 steps is needed for 9 am - 9 pm (same day) phase. The 1-hr cycling session will take place from 8 pm to 9 pm the second last day in the trial. A high fat tolerance test that lasts 5 hours will take place at 9 am the last day.

Group II: 24-hr trialExperimental Treatment1 Intervention

Participants will go through a 48-hr physical activity control phase with 10,000 steps taken every 24 hours (9 am to 9 am the next morning). This phase will be followed with a 24-hour physical inactive phase (9 am to 9 am the next morning). During this 24 hours, from 9 am to 9 pm (mostly daytime), less than 1,500 steps is required, and from 9 pm to 9 am the next morning (mostly night), less than 1,000 steps is required. The 1-hr cycling session will take place from 8 pm to 9 pm on the day when inactive phase starts. A high fat tolerance test that lasts 5 hours will take place at 9 am the last day.

Group III: 12-hr trialExperimental Treatment1 Intervention

Participants will go through a 48-hr physical activity control phase with 10,000 steps taken every 24 hours (9 pm to 9 pm the next day). This phase will be followed with a 12-hour physical inactive phase (9 pm to 9 am the next morning). Less than 1,000 steps during this 12 hours (mostly night time) will be required. The 1-hr cycling session will take place from 8 pm to 9 pm the same day when inactive phase starts. A high fat tolerance test that lasts 5 hours will take place at 9 am the last day.

0 / 3Eligibility criteria met

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Who is running the clinical trial?

University of Texas at AustinLead Sponsor

353 Previous Clinical Trials

81,232 Total Patients Enrolled

Jieting Wang, M.S.Principal InvestigatorThe University of Texas of Austin

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research program enrolling seniors above the age of seventy?

"This trial's criteria for enrollment stipulates that the lower limit of age is 18 and upper limit is 65."

Answered by AI

Who might be eligible to participate in this clinical research?

"To qualify for the clinical trial, participants must possess a normal metabolism and be within the bounds of 18 to 65 years old. Thus far, 12 individuals have been accepted into this medical research study."

Answered by AI

Is enrollment for this trial still available?

"As per clinicaltrials.gov, this specific investigation is not currently recruiting participants - the trial was posted on October 1st 2023 and last updated on September 13th of the same year. Nevertheless, there are 15 additional medical studies that currently need volunteers for their research projects."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Inactivity Duration on Lipid Metabolism

2023. "Inactivity Duration on Lipid Metabolism". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06033898.