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Physical Inactivity for Metabolism

N/A
Recruiting
Research Sponsored by University of Texas at Austin
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Healthy male or female between the age of 18-40 years old
No metabolic disease, no lactose intolerance, not taking medicines altering lipid or carbohydrate metabolism
Must not have
On medications that alter lipid or carbohydrate metabolism lactose intolerant
General health problems: Heart problems or coronary artery disease, hypertension, lung or respiratory problems
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, around 9 months
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to understand how being inactive for varying periods of time affects how the body processes fats after eating. They will measure blood fat levels and fat burning in healthy participants after they go through different periods

Who is the study for?
This trial is for healthy individuals interested in how different lengths of physical inactivity (4, 8, or 12 hours) affect their body's ability to manage fats after eating. Participants will need to be able to perform moderate cycling and follow a high-fat diet for the test.
What is being tested?
The study tests how periods of not moving much impact fat levels in blood and fat burning after exercise. Everyone does three trials with varying inactive times but also includes regular walking and cycling before a high-fat meal.
What are the potential side effects?
Since this trial involves common activities like sitting still, walking, cycling, and eating fatty foods, no significant side effects are expected beyond what might normally occur with these activities.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 40 years old and healthy.
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I don't have metabolic diseases, lactose intolerance, or take meds affecting my metabolism.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am lactose intolerant and on medication that affects my fat or sugar metabolism.
Select...
I have heart, lung, or high blood pressure issues.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, around 9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, around 9 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Fat oxidation (fat burning)
Plasma triglyceride

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: 8-hr TrialExperimental Treatment1 Intervention
Participants will go through a day of routine step counts and sleep hour monitor, 2 days of being physical active by taking ambulatory steps, 8 hours of physical inactivity intervention, and moderate intensity cycling, and 1 high fat tolerance test.
Group II: 4-hr trialExperimental Treatment1 Intervention
Participants will go through a day of routine step counts and sleep hour monitor, 2 days of being physical active by taking ambulatory steps, 4 hours of physical inactivity intervention, and moderate intensity cycling, and 1 high fat tolerance test.
Group III: 12-hr TrialExperimental Treatment1 Intervention
Participants will go through a day of routine step counts and sleep hour monitor, 2 days of being physical active by taking ambulatory steps, 12 hours of physical inactivity intervention, and moderate intensity cycling, and 1 high fat tolerance test.

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Who is running the clinical trial?

University of Texas at AustinLead Sponsor
374 Previous Clinical Trials
86,163 Total Patients Enrolled
1 Trials studying Metabolism
12 Patients Enrolled for Metabolism
~8 spots leftby Oct 2025
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