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Naturally-sweetened orange juice for Metabolic Syndrome (OASIS Trial)

N/A
Waitlist Available
Led By Kimber L Stanhope, Ph.D.
Research Sponsored by University of California, Davis
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 week
Awards & highlights

OASIS Trial Summary

This trial will study the effects of orange juice on metabolism compared to sugar-sweetened beverages.

Eligible Conditions
  • Metabolic Syndrome
  • Cardiovascular Risk
  • Type 2 Diabetes
  • Insulin Sensitivity

OASIS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Apolipoprotein B (apoB)
Endogenous glucose production
Hepatic triglyceride
+3 more
Secondary outcome measures
3-(3'-hydroxy-4'-methoxyphenyl)hydracrylic
Apolipoprotein C-II
Postprandial triglyceride
+3 more
Other outcome measures
Apolipoprotein E (apoE)
Body fat
Diastolic and systolic blood pressure
+26 more

OASIS Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Naturally-sweetened orange juiceExperimental Treatment1 Intervention
Naturally-sweetened orange juice Form: Beverage Daily dosage: 25% of daily energy requirement Frequency: Divided into 3 servings/day Duration: 4 weeks
Group II: Sugar-sweetened beverageActive Control1 Intervention
Sugar-sweetened beverage Form: Beverage Daily dosage: 25% of daily energy requirement Frequency: Divided into 3 servings/day Duration: 4 weeks

Find a Location

Who is running the clinical trial?

University of California, DavisLead Sponsor
910 Previous Clinical Trials
4,706,935 Total Patients Enrolled
12 Trials studying Metabolic Syndrome
616 Patients Enrolled for Metabolic Syndrome
Touro University, CaliforniaOTHER
7 Previous Clinical Trials
1,006 Total Patients Enrolled
Kimber L Stanhope, Ph.D.Principal InvestigatorUniversity of California, Davis
1 Previous Clinical Trials
36 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the eligibility for this research study limited to those aged 20 or younger?

"This clinical trial is aiming to enroll patients between 18 and 50 years old. For those below the age of consent, there are 156 other trials available while 1056 such options exist for senior citizens."

Answered by AI

Is it possible to become a participant in this medical experiment?

"For this clinical trial, 72 individuals aged 18-50 with metabolic syndrome must be recruited. Further requirements include a body mass index of 20-35 kg/m2 and a weight above 50kg; the patient should also have been maintaining their current weight for at least 6 months prior to enrolment."

Answered by AI

What is the aggregate amount of subjects participating in this evaluation?

"Affirmative. Clinicaltrials.gov data confirms that this medical research, which was first posted on June 1st 2018, is still recruiting participants. A total of 72 patients are sought after at a single centre."

Answered by AI

What benefits are expected to be yielded by this clinical investigation?

"This 4-week evaluation has been formulated to measure de novo lipogenesis (DNL). Other measures of interest include urine concentration of hesperetin-3'-O-glucuronide, plasma non-HDL cholesterol concentration, and postprandial triglycerides in the blood."

Answered by AI

Is this research project currently accepting participants?

"Affirmative. According to clinicaltrials.gov, this medical experiment is presently enrolling patients; it was first posted on June 1st 2018 and edited most recently on January 26th 2022. 72 participants are being recruited from a single site."

Answered by AI
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~8 spots leftby Apr 2025