Family Box Program for Cardiometabolic Diseases

Overseen By Madison N LeCroy, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: NYU Langone Health

Disqualifiers: Non-Chinese ethnicity, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 12

100 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help Chinese American families in New York City improve their diet and social bonds by providing boxes filled with whole grains, legumes, and educational materials that celebrate their cultural identity. The Family Box program seeks to reduce health issues like heart disease and diabetes in a culturally meaningful way. Families who are Chinese or Chinese American, have a child aged 2-6 living with them, and can pick up a box each month might be a good fit for this trial. As an unphased trial, this study offers a unique opportunity for families to enhance their health and cultural connections.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that the Family Box program is safe?

Research has shown that the Family Box program is safe for participants. The program offers culturally meaningful foods and educational materials to improve diet and strengthen family bonds. No reports of negative effects have emerged, as the program primarily involves dietary changes, which are generally safe. Without medications or medical procedures, the risk of side effects remains low. Participants can anticipate a positive experience centered on healthy eating and quality family time. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Family Box program for cardiometabolic diseases because it takes a unique, community-focused approach. Unlike traditional treatments that often focus on medication and individual lifestyle changes, this program provides culturally relevant resources directly to Chinese American families in New York City. By delivering boxes filled with ingredients, books, and educational materials tailored to their culture, the program aims to promote healthier family eating habits and lifestyle changes in a supportive, holistic way. This method could lead to more sustainable health outcomes by engaging the entire family in the process.

What evidence suggests that the Family Box program is effective for cardiometabolic diseases?

Research has shown that involving family can help manage health issues like type 2 diabetes and obesity. Families working together can better handle these conditions. In this trial, the Family Box Program will use family support to improve eating habits and social connections, aiding in disease management. Since these health problems often affect multiple family members, involving the whole family can be beneficial. Family support and cultural identity also impact heart health and disease outcomes. Overall, this program uses family and cultural ties to potentially improve health in meaningful ways. ^{2 6 7 8 9}

Who Is on the Research Team?

Madison N LeCroy, PhD

Principal Investigator

NYU Langone Health

Are You a Good Fit for This Trial?

This trial is for Chinese American families in NYC aiming to improve their diet and social bonds. It's designed to help with cardiometabolic diseases by providing whole grains, legumes, and fostering ethnic identity and resilience.

Inclusion Criteria

Self-identify as Chinese or Chinese American

I am a parent or caretaker of a child aged 2-6 who lives with me.

I am between 18 and 90 years old.

Exclusion Criteria

Individuals who don't meet the eligibility criteria

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive a monthly box with culturally relevant ingredients, books, and educational materials for 12 months

12 months

12 visits (monthly box delivery)

Follow-up

Participants are monitored for changes in diet and social cohesion after the intervention

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Family Box program

Trial Overview The 'Family Box program' is being tested, which offers subsidized produce boxes adapted to cultural preferences. The study evaluates if this can enhance diet quality and strengthen community ties among participants.

How Is the Trial Designed?

Group I: Chinese American families living in New York City (NYC) Experimental Treatment 1 Intervention

Participants will receive a box, once a month across one year for a total of 12 boxes, with culturally relevant ingredients, books, and educational materials.

Who Is Running the Clinical Trial?

NYU Langone Health

Lead Sponsor

Trials

1,431

Recruited

838,000+

National Institute on Minority Health and Health Disparities (NIMHD)

Collaborator

Trials

473

Recruited

1,374,000+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10590015/

Familial co-aggregation and shared genetics of ... Cardiometabolic disorders showed positive familial co-aggregation, particularly between T2D, MetS, and obesity.

2. onlinelibrary.wiley.com onlinelibrary.wiley.com/doi/full/10.1002/nop2.1858

Interventions for family support in cardiometabolic disease ... All studies demonstrated some level of the effectiveness for family involvement and support in the management of cardiometabolic diseases.

3. sciencedirect.com sciencedirect.com/science/article/pii/S0091743520300086

Results of a randomized controlled trial in primary care We aim to establish the effectiveness of a stepwise CMD risk assessment followed by individualized treatment if indicated compared to care as usual.

4. bmchealthservres.biomedcentral.com bmchealthservres.biomedcentral.com/articles/10.1186/s12913-025-12781-y

Policy models for preventative interventions in ... Cardiometabolic diseases (CMDs) are a leading cause of disability and mortality, as well as contributing to rising healthcare costs worldwide [1 ...

5. ahajournals.org ahajournals.org/doi/10.1161/JAHA.124.039031

Impact of Social Determinants of Health on Cardiovascular ... In conclusion, SDoHs significantly impact cardiovascular morbidity and death and specific outcomes of patients with cardiovascular disease.

6. withpower.com withpower.com/trial/phase-metabolic-syndrome-3-2025-75d37

Family Box Program for Cardiometabolic Diseases This N/A medical study run by NYU Langone Health is evaluating whether Family Box program will have tolerable side effects & efficacy for patients with ...

7. myhighplains.com myhighplains.com/business/press-releases/cision/20251105NY15585/novo-nordisk-presents-four-new-analyses-on-oral-semaglutide-25-mg-wegovy-in-a-pill-at-obesityweek-2025-including-demonstrated-reductions-in-cardiovascular-risk-factors

Novo Nordisk presents four new analyses on oral ... A cardiometabolic post hoc analysis from the OASIS 4 phase 3 clinical trial examined how the amount of weight patients lost affects glycemic ...

8. texasheartmedical.org texasheartmedical.org/our-specialties/cardiometabolic-syndrome-cms/

Cardiometabolic syndrome (CMS) Cardiometabolic syndrome (CMS), also known as metabolic syndrome, is a cluster of metabolic disorders that significantly increase a person's risk of ...

9. ahajournals.org ahajournals.org/doi/10.1161/cir.0000000000001184

Cardiovascular-Kidney-Metabolic Health: A Presidential ... This presidential advisory provides guidance on the definition, staging, prediction paradigms, and holistic approaches to care for patients with cardiovascular ...