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Polyphenols and Carotenoids

Mango consumption for Metabolic Syndrome

N/A
Waitlist Available
Led By Charles.Couillard@fsaa.ulaval.ca Couillard, PhD
Research Sponsored by Laval University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

Study Summary

This trial will study whether mangoes improve metabolic health by looking at changes in gut microbiota.

Eligible Conditions
  • Metabolic Syndrome
  • Gut Microbiome

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in plasma HDL cholesterol concentration of overweight/obese men and women taking frozen mangos daily
Changes in plasma LDL cholesterol concentration of overweight/obese men and women taking frozen mangos daily
Changes in plasma glucose concentration of overweight/obese men and women taking frozen mangos daily
+3 more
Secondary outcome measures
Changes in body mass index (BMI) of overweight/obese men and women taking frozen mangos daily
Changes in diastolic blood pressure of overweight/obese men and women taking frozen mangos daily
Changes in gene expression in peripheral blood mononuclear cells (PBMC) of overweight/obese men and women taking frozen mangos daily
+16 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Mango consumptionExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Laval UniversityLead Sponsor
417 Previous Clinical Trials
172,237 Total Patients Enrolled
26 Trials studying Metabolic Syndrome
2,000 Patients Enrolled for Metabolic Syndrome
Charles.Couillard@fsaa.ulaval.ca Couillard, PhDPrincipal InvestigatorLaval University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
Applied Physiology, Nutrition, and MetabolismJournal
Changes in Systolic Blood Pressure, Postprandial Glucose, and Gut Microbial Composition Following Mango Consumption in Individuals with Overweight and Obesity
Keathley, Justine, Michèle Kearney, Véronique Garneau, Juan de Toro-Martín, Thibault V. Varin, Geneviève Pilon, Patrick Couture, André Marette, Marie-Claude Vohl, and Charles Couillard. 2022. “Changes in Systolic Blood Pressure, Postprandial Glucose, and Gut Microbial Composition Following Mango Consumption in Individuals with Overweight and Obesity”. Applied Physiology, Nutrition, and Metabolism. Canadian Science Publishing. doi:10.1139/apnm-2021-0637.
Applied Physiology, Nutrition, and MetabolismJournal
Changes in Systolic Blood Pressure, Postprandial Glucose, and Gut Microbial Composition Following Mango Consumption in Individuals with Overweight and Obesity
Keathley, Justine, Michèle Kearney, Véronique Garneau, Juan de Toro-Martín, Thibault V. Varin, Geneviève Pilon, Patrick Couture, André Marette, Marie-Claude Vohl, and Charles Couillard. 2022. “Changes in Systolic Blood Pressure, Postprandial Glucose, and Gut Microbial Composition Following Mango Consumption in Individuals with Overweight and Obesity”. Applied Physiology, Nutrition, and Metabolism. Canadian Science Publishing. doi:10.1139/apnm-2021-0637.
Frontiers in NutritionJournal
Gene Expression Signatures and Cardiometabolic Outcomes Following 8-week Mango Consumption in Individuals with Overweight/obesity
Keathley, Justine, Juan de Toro-Martín, Michèle Kearney, Véronique Garneau, Geneviève Pilon, Patrick Couture, André Marette, Marie-Claude Vohl, and Charles Couillard. 2022. “Gene Expression Signatures and Cardiometabolic Outcomes Following 8-week Mango Consumption in Individuals with Overweight/obesity”. Frontiers in Nutrition. Frontiers Media SA. doi:10.3389/fnut.2022.918844.
clinicaltrials.govStudy
Effect of Mango on Gut Microbiota and Metabolic Health
Charles Couillard 2019. "Effect of Mango on Gut Microbiota and Metabolic Health". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03825276.
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