Your session is about to expire
← Back to Search
MRI for Peritoneal Mesothelioma
N/A
Waitlist Available
Led By Hedy Kindler, MD
Research Sponsored by University of Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Biopsy-proven MPM
18 years old or older
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 60 days
Awards & highlights
Study Summary
This trial is to test if new MRI and ultrasound techniques can detect cancer in the lining of the stomach better than current techniques.
Who is the study for?
This trial is for adults with biopsy-proven peritoneal mesothelioma who are planning surgery at UCM within 60 days. They must be able to undergo CT, MRI, and ultrasound scans as well as surgery. Women of childbearing age should commit to using contraception for a year after imaging.Check my eligibility
What is being tested?
Researchers are testing new experimental MRI and ultrasound techniques against standard CT imaging to see if they can better detect cancer spread in the stomach lining caused by mesothelioma.See study design
What are the potential side effects?
There may not be direct side effects from the imaging techniques themselves, but participants might experience discomfort or anxiety during long scanning sessions. Allergic reactions to contrast dyes used in these scans could also occur.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
My diagnosis of mesothelioma was confirmed through a biopsy.
Select...
I am 18 years old or older.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 60 days
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 days
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Higher Sensitivity for detection using New High Resolution Contrast Enhanced MRI Imaging Sequences compared to standard MRI
Higher sensitivity for detection of peritoneal metastatic disease using Ultrasound Elastography compared to standard MRI
Secondary outcome measures
Perform Ultrasound Elastography in peritoneal mesothelioma to determine elasticity scores
Perform Ultrasound Elastography in peritoneal mesothelioma to determine optimal strain ratios
Test high-definition small-voxel MRI imaging sequences for detection of peritoneal disease in MPM
+1 moreTrial Design
2Treatment groups
Experimental Treatment
Group I: Testing Phase- Conventional and HR-MRI and UltrasoundExperimental Treatment2 Interventions
Patients will undergo conventional and HR-MRI imaging as well as abdominal ultrasound to define the performance of these methods.
Group II: Exploratory Phase - Standard CT Imaging and HR-MRIExperimental Treatment2 Interventions
The goal is to test several different novel Magnetic Resonance sequences to determine which gives the best visualization of peritoneal disease.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ultrasound
2013
Completed Phase 1
~1950
Find a Location
Who is running the clinical trial?
University of ChicagoLead Sponsor
1,003 Previous Clinical Trials
819,723 Total Patients Enrolled
1 Trials studying Peritoneal Mesotheliomas
2 Patients Enrolled for Peritoneal Mesotheliomas
Hedy Kindler, MDPrincipal InvestigatorUniversity of Chicago
1 Previous Clinical Trials
15 Total Patients Enrolled
Kiran Turaga, MDPrincipal InvestigatorUniversity of Chicago
4 Previous Clinical Trials
395 Total Patients Enrolled
1 Trials studying Peritoneal Mesotheliomas
2 Patients Enrolled for Peritoneal Mesotheliomas
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I cannot lie flat due to breathing or heart problems.I have heart, circulation, or sweating issues affecting my body's temperature control.I cannot have CT or MRI scans due to kidney problems.You have surgical implants that are not safe for MRI scans.I can undergo CT, MRI, US scans, and surgery without issues.You are allergic to contrast dyes used in medical tests.You have permanent tattoos or eyeliner with magnetic dyes.You have metal pieces in your body from an injury.You have medical devices that can't be used during MRI scans, like cochlear implants, pacemakers, or certain types of pumps and stimulators.You have any other metal implant in your body that could be harmed by an MRI.My diagnosis of mesothelioma was confirmed through a biopsy.I am able to understand and follow the treatment plan.You have anxiety, claustrophobia, or any medical condition that would make it difficult for you to stay still in an MRI scanner for 1-1.5 hours.I cannot hold my breath for an MRI scan.I am scheduled for surgery at UCM within the next 60 days.I am 18 years old or older.I have had surgery before that changed the lining of my abdomen.
Research Study Groups:
This trial has the following groups:- Group 1: Testing Phase- Conventional and HR-MRI and Ultrasound
- Group 2: Exploratory Phase - Standard CT Imaging and HR-MRI
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How many participants are being allowed to take part in this trial?
"Affirmative. The records available on clinicaltrials.gov confirm that this medical research, which was initially posted in October 2018, is currently recruiting subjects. 24 participants will be admitted from a single study centre."
Answered by AI
What goals are researchers attempting to accomplish with this clinical experiment?
"This 60-day trial aims to improve sensitivity of diagnosis using high resolution contrast enhanced MRI imaging sequences. Additionally, it will assess ultrasound elastography in order to ascertain optimal strain ratios and elasticity scores that can optimise accuracy for peritoneal mesothelioma patients. Finally, the experiment would test HD small-voxel MRIs focusing on right hemidiaphragmatic and pelvic spaces to detect malignant disease."
Answered by AI
Is it still feasible to join this experimental endeavor?
"Affirmative, the information hosted by clinicaltrials.gov specifies that this trial is presently in search of candidates. This study was first denoted on October 10th 2018 and last modified on May 16th 2022; 24 patients are desired for enrollment at a single site."
Answered by AI
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger