What side effects are associated with this type of intervention?

Common treatments for mental illness, particularly those integrated in models like the Integrated Collaborative Care Team (ICCT), include pharmacological and psychotherapeutic interventions. Pharmacological treatments, such as SSRIs and SNRIs, can cause side effects like nausea, weight gain, sexual dysfunction, and insomnia. Psychotherapeutic interventions, including CBT and DBT, generally have fewer physical side effects but may cause emotional discomfort as patients work through challenging issues. The ICCT model aims to integrate these treatments, potentially reducing some side effects through comprehensive, coordinated care.

What prior FDA approvals exist?

The FDA has approved several medications for the treatment of mental illnesses that are often used in collaborative care settings. For depression, common FDA-approved medications include selective serotonin reuptake inhibitors (SSRIs) like fluoxetine and sertraline, and serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine and duloxetine. For anxiety disorders, SSRIs and benzodiazepines such as alprazolam and diazepam are frequently prescribed. In the treatment of schizophrenia, antipsychotics like risperidone, olanzapine, and aripiprazole are commonly used. These medications are often integrated into collaborative care models that involve coordinated efforts between primary care providers, mental health specialists, and community resources to ensure comprehensive and timely access to care.

What other types of research exist?

Promising, novel alternatives to the Integrated Collaborative Care Team (ICCT) model for mental illness patients include: 1) Cognitive Behavioral Therapy (CBT) programs like Reasoning and Rehabilitation 2, which address multiple symptomatic or deficit targets of ADHD with multimodal interventions. 2) Adapted Dialectical Behavior Therapy (DBT) for adult ADHD, which includes modules on emotional awareness, regulation, and mindfulness. 3) Community Reinforcement Approach (CRA) for substance use disorders, which incorporates CBT components and principles to address a wider variety of issues in recovery. 4) Behavioral Couples Therapy (BCT) for substance use disorders, which addresses problematic behaviors within committed relationships that sustain substance use and inhibit recovery.

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Integrated Collaborative Care for Youth Mental Health and Addiction

N/A

Waitlist Available

Led By Joanna Henderson, Ph.D., C.Psych

Research Sponsored by Centre for Addiction and Mental Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged 14 - 17 years 11 months

Be younger than 65 years old

Must not have

Primary diagnosis of an eating disorder

Timeline

Screening 3 weeks

Treatment Varies

Follow Up one year

Awards & highlights

No Placebo-Only Group

Summary

This trial tests a new way of providing mental health and addiction services for young people aged 14-18. The Integrated Collaborative Care Team (ICCT) model involves a team of healthcare providers working together to offer fast and personalized care. The goal is to improve mental health outcomes, reduce waiting times, and be more cost-effective compared to usual treatments.

Who is the study for?

This trial is for youth aged 14-17 with mental health and addiction challenges seeking outpatient services in Toronto. They must consent to the study, be new referrals to participating hospitals, and able to read/write English. Those with active psychosis, immediate self-harm risk, or needing specialty treatments are excluded.

What is being tested?

The study compares usual hospital treatment (TAU) against a new model called Integrated Collaborative Care Team (ICCT), which offers rapid access to mental health and addiction services in a youth-friendly environment. The goal is better outcomes and more efficient care.

What are the potential side effects?

Since this trial involves service models rather than medications, there aren't typical side effects like you'd see with drugs. However, participants may experience varying levels of comfort or satisfaction with the services received.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 14 and 17 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I have been diagnosed with an eating disorder.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ one year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~one year

This trial's timeline: 3 weeks for screening, Varies for treatment, and one year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Youth functioning

Secondary study objectives

Caregiver burden

Client empowerment and engagement

Clinical improvement

+6 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Integrated Collaborative Care TeamExperimental Treatment1 Intervention

Integrated Collaborative Care Team (ICCTs) are housed in the local community to improve youth access, in three neighborhoods across Toronto (East Metro Youth Services \[EMYS\]-Scarborough, EMYS-Southeast Toronto, and Delisle Youth Services-Central Toronto). Each ICCT will include a variety of service providers and coordinated patient care delivering evidence-informed interventions in a stepped-care model.

Group II: Treatment as Usual (TAU)Active Control1 Intervention

The comparator arm consists of out-patient TAU in a hospital setting and will occur at one of four outpatient hospital sites across Toronto. Partners include the following four hospitals: Hospital for Sick Children (SickKids), the Centre for Addiction and Mental Health (CAMH), Michael Garron Hospital (formerly the Toronto East General Hospital), and Sunnybrook Hospital.

0 / 2Eligibility criteria met

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

The Integrated Collaborative Care Team (ICCT) model for treating mental illness focuses on rapid, systematic access to a combination of pharmacotherapy, psychotherapy, and psychosocial interventions through community and healthcare partnerships. Pharmacotherapy addresses neurotransmitter imbalances, psychotherapy helps patients develop coping strategies and change negative thought patterns, and psychosocial interventions improve social functioning and support systems. This integrated approach ensures timely access to comprehensive care, which is essential for improving mental health outcomes and reducing the burden on patients and their families.

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