Tailored Mindfulness Program for Fear of Memory Loss for Memory Loss

1
Effectiveness
1
Safety
Northwestern University, Chicago, IL
Memory Loss+1 More
Tailored Mindfulness Program for Fear of Memory Loss - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Memory Loss

Study Summary

This study is evaluating whether a web-based mindfulness program can help reduce anxiety and increase quality of life for older adults with dementia-related fears.

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Eligible Conditions

  • Memory Loss
  • Memory Disorders
  • Anxiety and Fear

Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Tailored Mindfulness Program for Fear of Memory Loss will improve 2 primary outcomes and 5 secondary outcomes in patients with Memory Loss. Measurement will happen over the course of Follow-up (4 weeks).

10 Week Post-Baseline
Memory Failure Scale (MFS)
10 Weeks Post-Baseline
Change of Fear and Avoidance of Memory Loss (FAM) Scale score at follow-up
Change of Fear of Alzheimer's Disease Scale (FADS) score at follow-up
Coronavirus Anxiety Scale (CAS)
Patient Reported Outcome Measures Information System-29 (PROMIS-29)
World Health Organization Well-Being Index (WHO-5)
Follow-up (4 weeks)
Patient Global Impression of Change (PGIC)

Trial Safety

Safety Estimate

1 of 3

Trial Design

2 Treatment Groups

Conventional Mindfulness Program
Tailored Mindfulness Program for Fear of Memory Loss

This trial requires 80 total participants across 2 different treatment groups

This trial involves 2 different treatments. Tailored Mindfulness Program For Fear Of Memory Loss is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Tailored Mindfulness Program for Fear of Memory Loss
Behavioral
Tailored mindfulness lessons and activities for fear of memory loss.
Conventional Mindfulness Program
Behavioral
Routine mindfulness lessons and activities.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 10 week post-baseline
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 10 week post-baseline for reporting.

Who is running the study

Principal Investigator
J. W. G.
Prof. James W Griffith, Associate Professor
Northwestern University

Closest Location

Northwestern University - Chicago, IL

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 6 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
55 years of age or older
Elevated dementia-related fear
Able to read/write in English
Willingness to be randomized to intervention group
Willingness to complete three weeks of self-guided intervention, questionnaires, and cognitive tests.
Access to a reliable internet connection

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many people get memory loss a year in the United States?

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Approximately half of men and almost 1/3 of women experience noticeable forgetfulness. However, it is hard to know how many people have or are experiencing memory loss and how common it is for people to find help. As the population ages, it will become important to evaluate the mental wellness of aging people to determine if these complaints are caused by normal aging, age-related medical conditions, or depression. The lack of data on memory loss may be attributed to the fact that people often choose not to report trouble with memory.

Unverified Answer

What is memory loss?

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This is the first study done in Iran in order to explore the impact of hyperglycemia on spatial memory and attention. The present study revealed that hyperglycemia with diabetes mellitus (DM) is associated with lower attention at the short and longer latency duration interval tests in spatial memory performance, but the results did not meet the criteria for significant significance. Moreover, it was concluded that hyperglycemia was associated with a decline in spatial working memory, but the magnitude and duration of the decline was not significant. The authors suggested that further studies are needed to determine the relationship between spatial memory and hyperglycemia.

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What are the signs of memory loss?

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There are no specific tests that assess for memory deficits. However, memory impairment in individuals over the age of 50 is often noticeable. For example, memory loss may cause confusion with dementia. Older adults may have difficulty retaining information and putting it to use. Therefore, individuals over the age of 50 should be screened for cognitive decline. This article will offer a systematic approach for screening for older adults with memory complaints.

Unverified Answer

What causes memory loss?

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It is not currently known what causes memory loss. It can occur naturally or be caused by a number of other factors. Because of this, there is research on reversing memory loss, such as the use of a healthy lifestyle.\n

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Can memory loss be cured?

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Memory loss is a significant cause of morbidity and mortality in the general age span and can be relieved to some extent by treatment with selective serotonin reuptake inhibitors, antidepressants or dopamine agonists, even after 10 years. Thus, memory loss is not a permanent condition and is not necessarily incurable. While medication is not an effective cure in the long-term, it may improve symptoms in the short-term.

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What are common treatments for memory loss?

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Treatment must be tailored to the individual, and may include medications, physical therapy, and cognitive-behavioral therapy (CBT). Antidepressants are of questionable benefit, and more long-term trials are needed. Patients with significant depression are at risk of further psychological harm or even suicide.

Unverified Answer

What is the primary cause of memory loss?

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While there is a small group of primary causes of memory loss, a strong correlation was found between two of these and memory loss in the entire group. These factors include smoking, hypertension, hyperglycemia, and hyperlipidemia. The prevalence of memory loss between groups was not significantly different. Primary causes of memory loss have not been previously reported previously in medical literature. This correlation is indicative of possible causal or causal relationships between memory loss and primary disease conditions. One of these conditions may be the result of the other. The exact relationship between memory loss and hypertension needs to be elucidated by further study.

Unverified Answer

Is tailored mindfulness program for fear of memory loss typically used in combination with any other treatments?

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Self-monitoring is only commonly used in combination with other treatments while mindfulness training is not. Both mindfulness and self-monitoring has been proven effective in reducing fear of cognitive decline in healthy elderly.

Unverified Answer

What does tailored mindfulness program for fear of memory loss usually treat?

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This pilot study adds further evidence to tailored mindfulness-based self-care program for fear of memory loss. Further studies are necessary to establish the benefits and maintenance of this intervention for a large-group patients.

Unverified Answer

Does memory loss run in families?

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The present study suggests that there is a strong correlation between an individual's genotype for GABRA5 and their age-related cognitive function. In addition, there was also a strong correlation between GABRA5 rs3212887 genotype and their parents' chronological age, suggesting that there is also a strong familial component for age-related cognitive deficits.

Unverified Answer

What is the latest research for memory loss?

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The evidence, as it stands at present, says that there is no evidence that memory loss is a permanent loss. The key factors that determine whether people lose memory are that it is either a progressive deterioration or a functional decline over time. The evidence also suggests that there is scope for improving health care efficiency by reducing the number of people with mild or reversible impairment who are denied treatment unnecessarily.

Unverified Answer

Who should consider clinical trials for memory loss?

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Memory loss patients with mild to moderate disease had a poor prognosis; however, patients with severe or advanced disease were able to benefit from clinical trials. Thus, memory loss symptoms should not be an absolute contraindication to clinical trial participation for patients with multiple sclerosis.

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See if you qualify for this trial
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