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Interferon

Treatment (interferon therapy) for Skin Melanoma

N/A
Waitlist Available
Led By William Carson, MD
Research Sponsored by William Carson
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 1 year
Awards & highlights

Study Summary

This pilot clinical trial studies recombinant interferon alfa-2b in treating patients with melanoma. Recombinant interferon alfa-2b may interfere with the growth of tumor cells and slow the growth of melanoma

Eligible Conditions
  • Skin Melanoma
  • Melanoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Level of Activated STAT1(Phospho-STAT1)
Secondary outcome measures
Clinical Role of Tumor Sensitivity to Recombinant Interferon Alfa-2b Using Cellular Levels of Jak-STAT Signaling Intermediates
Effect of Dose-reduction on Expression of Interferon Alfa Stimulated Genes
Effect of Dose-reduction on Interferon Alfa Gene Expression
+4 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Treatment (interferon therapy)Experimental Treatment2 Interventions
Patients receive recombinant interferon alfa-2b SC thrice weekly. Treatment continues for 11 months in the absence of disease progression or unacceptable toxicity.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Interferon alfa-2b
FDA approved

Find a Location

Who is running the clinical trial?

Schering-PloughIndustry Sponsor
162 Previous Clinical Trials
41,486 Total Patients Enrolled
William CarsonLead Sponsor
2 Previous Clinical Trials
5 Total Patients Enrolled
William Carson, MDPrincipal InvestigatorOhio State University
5 Previous Clinical Trials
220 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma
William Carson 2008. "Recombinant Interferon Alfa-2b in Treating Patients With Melanoma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01460875.
~2 spots leftby May 2025
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