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Cannabinoid Withdrawal Treatment

Abstinent for Cognitive Impairment

N/A
Waitlist Available
Led By Randi M Schuster, PhD
Research Sponsored by Massachusetts General Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1, 2, 3, and 4 weeks
Awards & highlights

Study Summary

This trial will test if not using cannabis for 30 days leads to better cognitive functioning than just being monitored for 30 days.

Eligible Conditions
  • Cognitive Impairment
  • Cannabis Use
  • Adolescent Behaviors

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1, 2, 3, and 4 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1, 2, 3, and 4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mean Difference in First Attempt Memory Score From Paired Associates Learning (PAL) Module Averaged Over Weeks 1, 2, 3, and 4
Mean Difference in Forward Span Length From Spatial Span (SSP) Module Averaged Over Weeks 1, 2, 3, and 4
Mean Difference in Number of Problems Correctly Solved on the First Choice From the One Touch Stockings of Cambridge (OTS) Module Averaged Over Weeks 1, 2, 3, and 4
+14 more
Secondary outcome measures
Mean Difference in the Measure of Discriminability - A' From the Rapid Visual Information Processing (RVP) Module Averaged Over Weeks 1, 2, 3, and 4
Mean Difference in the Reponse Latency for Hits From the Rapid Visual Information Processing (RVP) Module Averaged Over Weeks 1, 2, 3, and 4

Trial Design

3Treatment groups
Active Control
Group I: AbstinentActive Control1 Intervention
This group of cannabis users are agree to remain abstinent from cannabis use for 30 days.
Group II: Non-UsersActive Control1 Intervention
This is a group of adolescents with little to no cannabis use history and is non-randomized.
Group III: MonitoringActive Control1 Intervention
This group of cannabis users are not asked to change their cannabis use behavior.

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor
2,928 Previous Clinical Trials
13,198,154 Total Patients Enrolled
Randi M Schuster, PhDPrincipal InvestigatorMassachusetts General Hospital
3 Previous Clinical Trials
19,206 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Cognitive Recovery With Cannabis Abstinence Among High School-Aged Adolescents
Randi Melissa Schuster 2017. "Cognitive Recovery With Cannabis Abstinence Among High School-Aged Adolescents". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03276221.
~26 spots leftby Apr 2025
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