Cognitive Intervention for Lupus
(CCIC Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial focuses on supporting brain health in young people with childhood-onset lupus. Researchers are testing a new online program, the Lupus Teen Online Problem Solving program, which aims to help teens with lupus manage cognitive challenges. Participants should have had a lupus diagnosis for some time and often experience difficulties with mental tasks. The trial seeks individuals who can access technology to join the virtual program. As an unphased trial, this study provides a unique opportunity for teens to access innovative support tools that could enhance their cognitive health.
What prior data suggests that the Lupus Teen Online Problem Solving program is safe for children and youth with childhood-onset lupus?
Research has shown that the Lupus Teen Online Problem Solving program is generally safe for young people with lupus. Studies have found that this program, which includes therapy sessions, can be helpful without causing harm. Recent research highlights that a six-session online therapy course can greatly improve the lives of children and teenagers with lupus. No reports of negative effects have emerged from participating in these therapy sessions. Overall, the program appears well-received and is designed to support brain health in young patients.12345
Why are researchers excited about this trial?
Researchers are excited about the Lupus Teen Online Problem Solving program because it offers a unique approach to managing cognitive issues associated with lupus, especially in teens. Unlike conventional treatments that mainly focus on controlling physical symptoms with medications like corticosteroids or immunosuppressants, this program targets cognitive and psychological challenges through an interactive online platform. By using problem-solving techniques tailored for teens, it aims to enhance mental function and quality of life, providing a supportive and engaging way to address an often-overlooked aspect of lupus care.
What evidence suggests that the Lupus Teen Online Problem Solving program is effective for childhood-onset lupus?
Research has shown that self-management programs can assist people with lupus. Programs such as the TEACH program have successfully helped young lupus patients manage their symptoms. These programs often teach coping skills to enhance mental health and overall quality of life. Additionally, studies have found that online programs increase knowledge about lupus and promote healthier behaviors. This trial will evaluate the Lupus Teen Online Problem Solving program, which may help young patients manage childhood-onset lupus more effectively.56789
Who Is on the Research Team?
Busi Zapparoli, PhD
Principal Investigator
The Hospital for Sick Children
Andrea Knight, MD, MSCE
Principal Investigator
The Hospital for Sick Children
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention Development
Development of a tailored brain health intervention for cSLE patients using a patient-informed participatory action approach
Intervention Implementation
Implementation of the brain health intervention and assessment of feasibility and acceptability
Follow-up
Participants are monitored for safety and effectiveness after intervention completion, including qualitative feedback and acceptability ratings
What Are the Treatments Tested in This Trial?
Interventions
- Lupus Teen Online Problem Solving program
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Andrea Knight
Lead Sponsor
The Hospital for Sick Children
Collaborator
Citations
Effective Self-Management Interventions for Patients With Lupus
This article presents the argument that peer mentoring may be an especially effective intervention approach for AA women with SLE.
2.
humanmedicine.msu.edu
humanmedicine.msu.edu/news/2026-teach-program-helps-young-lupus-patients-better-manage-symptoms.htmlTherapy Program for Kids with Lupus Can Change Lives in 6 ...
The effectiveness of the TEACH program was recently evaluated in young lupus patients and the results are published in Arthritis Care and ...
Funded Research in Childhood Lupus
For teens with lupus, mastering disease self-management is a crucial process required to successfully transition to independent, adult care and to prevent ...
4.
acrabstracts.org
acrabstracts.org/abstract/assessing-the-reach-of-a-virtual-education-program-lupus-you-answers-advocacy-action/Assessing the Reach of a Virtual Education Program
L&Y is a free educational series where people with lupus and their family and friends can learn more about the latest in lupus research and disease management.
5.
lupustherapeutics.org
lupustherapeutics.org/promising-data-shows-lupus-research-alliance-peer-education-program-increases-intentions-to-join-clinical-trials-among-diverse-patient-population/Promising Data Shows Lupus Research Alliance Peer ...
Promising Data Shows Lupus Research Alliance Peer Education Program Increases Intentions to Join Clinical Trials Among Diverse Patient ...
The unique challenges of childhood-onset systemic lupus ...
In this comprehensive review of the literature, we synthesize the obstacles adolescents and young adults (AYA) with systemic lupus erythematosus ...
Therapy program for kids with lupus can change lives in 6 ...
New research led by a Michigan State University scientist shows that a six-session remote psychological therapy program can help young lupus ...
The Expert Series: Lupus and Teens
In this episode of our podcast, we talk to Dr. Tamar Rubinstein about how lupus affects teenagers, how they can cope with lupus and more.
9.
msutoday.msu.edu
msutoday.msu.edu/news/2026/04/program-for-kids-with-lupus-can-change-lives-in-6-sessionsProgram for kids with lupus can change lives in 6 sessions
New research led by a Michigan State University scientist shows that a six-session remote psychological therapy program can help young lupus ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.