Educational Intervention for Lung Cancer

MT
Overseen ByMatthew Triplette, MD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Fred Hutchinson Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This clinical trial develops and studies whether a restorative justice-based lung cancer screening (LCS) decision-making support intervention tailored for Black individuals increases LCS among Black community members. Lung cancer remains the leading cause of cancer deaths among Black men and women. LCS with yearly low-dose chest computed tomography (CT) is recommended for people with current or recent tobacco use (within 15 years) who are aged 50-80 with at least a 20 pack-year smoking history. LCS lowers lung cancer death by 20%; however, data shows that LCS completion remains low among minority groups in the United States. The restorative justice-based LCS decision-making support intervention in this trial has been specifically tailored to meet the needs of Black individuals. It is designed to reduce racial unfairness by promoting trust, shared understanding, and empowerment in clinical decision making while addressing the social and historical circumstances of health inequalities. This may be an effective way to increase LCS among Black community members.

Who Is on the Research Team?

MT

Matthew Triplette, MD, MPH

Principal Investigator

Fred Hutch/University of Washington Cancer Consortium

Are You a Good Fit for This Trial?

Inclusion Criteria

Proficiency in the English language
Self-reported 20-pack year smoking history
Identify as Black or African American
See 4 more

Exclusion Criteria

Non-English speaking community advisory board (CAB) members
Inability to read written English
I am under 18 years old.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Community Advisory Board Meetings

Participants attend CAB meetings over 60 minutes on study in support of the co-development and adaptation of the restorative justice-based LCS decision-making support intervention.

1 session
1 visit (in-person)

Intervention

Participants attend an in-person restorative justice-based LCS decision-making support session over 2-3 hours on study.

1 session
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including completion of chest CT within 90 days post-intervention.

Up to 90 days

What Are the Treatments Tested in This Trial?

Interventions

  • Restorative Justice-Based Lung Cancer Screening Decision-Making Support Intervention

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Aim 2: Lung cancer screening (LCS) decision-making support session (intervention)Experimental Treatment4 Interventions
Group II: Aim 1: Community advisory board (CAB) meetingsActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Fred Hutchinson Cancer Center

Lead Sponsor

Trials
583
Recruited
1,341,000+

Go2 Foundation

Collaborator

AstraZeneca

Industry Sponsor

Trials
4,491
Recruited
290,540,000+

Sir Pascal Soriot

AstraZeneca

Chief Executive Officer since 2012

Veterinary Medicine from École nationale vétérinaire d'Alfort, MBA from HEC Paris

Dr. Cristian Massacesi

AstraZeneca

Chief Medical Officer since 2021

MD from Marche Polytechnic University, Oncology training at Royal Marsden Hospital, Kaplan Comprehensive Cancer Center, and European Institute of Oncology

Pascal Soriot

AstraZeneca

Chief Executive Officer since 2012

Veterinary Medicine from École nationale vétérinaire d'Alfort, MBA from HEC Paris

Cristian Massacesi

AstraZeneca

Chief Medical Officer since 2021

MD from Marche Polytechnic University, Medical Oncology training at Royal Marsden Hospital, Kaplan Comprehensive Cancer Center, and European Institute of Oncology